Melphalan and its role in the management of patients with multiple myeloma.
about
The glutathione synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma.First-in-human, phase I/IIa clinical study of the peptidase potentiated alkylator melflufen administered every three weeks to patients with advanced solid tumor malignancies.Drug resistance and cellular adaptation to tumor acidic pH microenvironmentMixed ligand copper(II) dicarboxylate complexes: the role of co-ligand hydrophobicity in DNA binding, double-strand DNA cleavage, protein binding and cytotoxicity.Induction of chemoresistance by all-trans retinoic acid via a noncanonical signaling in multiple myeloma cells.Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1 in the resistance to melphalan in multiple myeloma.Preclinical and clinical evaluation of elotuzumab, a SLAMF7-targeted humanized monoclonal antibody in development for multiple myeloma.Nuclease and anti-proliferative activities of copper(II) complexes of N3O tripodal ligands involving a sterically hindered phenolate.Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cellsMelflufen - a peptidase-potentiated alkylating agent in clinical trials.Covalent adducts of melphalan with free amino acids and a model peptide studied by liquid chromatography/tandem mass spectrometry.
P2860
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P2860
Melphalan and its role in the management of patients with multiple myeloma.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Melphalan and its role in the management of patients with multiple myeloma.
@en
type
label
Melphalan and its role in the management of patients with multiple myeloma.
@en
prefLabel
Melphalan and its role in the management of patients with multiple myeloma.
@en
P2093
P2860
P356
P1476
Melphalan and its role in the management of patients with multiple myeloma
@en
P2093
Fortunato Morabito
Ilaria Avonto
Mario Boccadoro
Patrizia Falco
Sara Bringhen
P2860
P304
P356
10.1586/14737140.7.7.945
P577
2007-07-01T00:00:00Z