The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development
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The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activityLIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencingMechanosensitivity and compositional dynamics of cell-matrix adhesionsLIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implicationsMigfilin and filamin as regulators of integrin activation in endothelial cells and neutrophils.Promoter hypermethylation-induced transcriptional down-regulation of the gene MYCT1 in laryngeal squamous cell carcinomaA screen identifies the oncogenic micro-RNA miR-378a-5p as a negative regulator of oncogene-induced senescence.Gene expression profiling identifies IRF4-associated molecular signatures in hematological malignanciesRHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect.Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis.Genetic and epigenetic changes in lung carcinoma and their clinical implications.The hypoxic tumor microenvironment: driving the tumorigenesis of non-small-cell lung cancer.LIMD1 antagonizes E2F1 activity and cell cycle progression by enhancing Rb function in cancer cells.PU.1 is a major transcriptional activator of the tumour suppressor gene LIMD1.A novel 3p22.3 gene CMTM7 represses oncogenic EGFR signaling and inhibits cancer cell growth.Differential transmission of the molecular signature of RBSP3, LIMD1 and CDC25A in basal/ parabasal versus spinous of normal epithelium during head and neck tumorigenesis: A mechanistic study.In vivo cardiac role of migfilin during experimental pressure overload.Loss of heterozygosity and methylation of multiple tumor suppressor genes on chromosome 3 in hepatocellular carcinoma.LIMD1 is a survival prognostic marker of gastric cancer and hinders tumor progression by suppressing activation of YAP1
P2860
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P2860
The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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The chromosome 3p21.3-encoded ...... human lung cancer development
@en
The chromosome 3p21.3-encoded ...... human lung cancer development.
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type
label
The chromosome 3p21.3-encoded ...... human lung cancer development
@en
The chromosome 3p21.3-encoded ...... human lung cancer development.
@nl
prefLabel
The chromosome 3p21.3-encoded ...... human lung cancer development
@en
The chromosome 3p21.3-encoded ...... human lung cancer development.
@nl
P2093
P2860
P356
P1476
The chromosome 3p21.3-encoded ...... human lung cancer development
@en
P2093
Ahmad Al-Attar
Aldi Kraja
Andrew G Nicholson
Daniel E Foxler
Elaine Mardis
Gregory D Longmore
Hala S Nijmeh
John Osborne
Qunyuan Zhang
P2860
P304
19932-19937
P356
10.1073/PNAS.0805003105
P407
P577
2008-12-05T00:00:00Z