The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development - Wikidata - wikimedia - TriplyDB

The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development

The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development

http://www.wikidata.org/entity/Q37018751

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The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing Mechanosensitivity and compositional dynamics of cell-matrix adhesions LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implications Migfilin and filamin as regulators of integrin activation in endothelial cells and neutrophils.Promoter hypermethylation-induced transcriptional down-regulation of the gene MYCT1 in laryngeal squamous cell carcinoma A screen identifies the oncogenic micro-RNA miR-378a-5p as a negative regulator of oncogene-induced senescence.Gene expression profiling identifies IRF4-associated molecular signatures in hematological malignancies RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect.Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis.Genetic and epigenetic changes in lung carcinoma and their clinical implications.The hypoxic tumor microenvironment: driving the tumorigenesis of non-small-cell lung cancer.LIMD1 antagonizes E2F1 activity and cell cycle progression by enhancing Rb function in cancer cells.PU.1 is a major transcriptional activator of the tumour suppressor gene LIMD1.A novel 3p22.3 gene CMTM7 represses oncogenic EGFR signaling and inhibits cancer cell growth.Differential transmission of the molecular signature of RBSP3, LIMD1 and CDC25A in basal/ parabasal versus spinous of normal epithelium during head and neck tumorigenesis: A mechanistic study.In vivo cardiac role of migfilin during experimental pressure overload.Loss of heterozygosity and methylation of multiple tumor suppressor genes on chromosome 3 in hepatocellular carcinoma.LIMD1 is a survival prognostic marker of gastric cancer and hinders tumor progression by suppressing activation of YAP1

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The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development

http://www.wikidata.org/entity/Q37018751

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 05 December 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The chromosome 3p21.3-encoded ...... human lung cancer development

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The chromosome 3p21.3-encoded ...... human lung cancer development.

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The chromosome 3p21.3-encoded ...... human lung cancer development

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The chromosome 3p21.3-encoded ...... human lung cancer development.

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prefLabel

The chromosome 3p21.3-encoded ...... human lung cancer development

@en

The chromosome 3p21.3-encoded ...... human lung cancer development.

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PNAS.0805003105

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Proceedings of the National Academy of Sciences of the United States of America

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The chromosome 3p21.3-encoded ...... human lung cancer development

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Ahmad Al-Attar

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Aldi Kraja

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Andrew G Nicholson

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Daniel E Foxler

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Elaine Mardis

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Gregory D Longmore

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Hala S Nijmeh

http://www.w3.org/2001/XMLSchema#string

John Osborne

http://www.w3.org/2001/XMLSchema#string

Li Ding

http://www.w3.org/2001/XMLSchema#string

Qunyuan Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

A novel gene containing LIM domains (LIMD1) is located within the common eliminated region 1 (C3CER1) in 3p21.3

LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription

The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin

Characterizing the cancer genome in lung adenocarcinoma.

CpG islands in vertebrate genomes

A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies

The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast development

Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers.

Search for unknown tumor-antagonizing genes.

3p21.3 tumor suppressor cluster: prospects for translational applications.

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19932-19937

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scholarly article

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10.1073/PNAS.0805003105

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105

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2008-12-05T00:00:00Z

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23627276

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19060205

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2604919

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