Synonymous mutations and ribosome stalling can lead to altered folding pathways and distinct minima.
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The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutationsDecoding mechanisms by which silent codon changes influence protein biogenesis and functionA Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-CellsA gene optimization strategy that enhances production of fully functional P-glycoprotein in Pichia pastorisImpairment of translation in neurons as a putative causative factor for autismA multiparametric computational algorithm for comprehensive assessment of genetic mutations in mucopolysaccharidosis type IIIA (Sanfilippo syndrome)Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression DefectThe silent codon change I507-ATC->ATT contributes to the severity of the ΔF508 CFTR channel dysfunctionRPLP1 and RPLP2 Are Essential Flavivirus Host Factors That Promote Early Viral Protein AccumulationA synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.How the Sequence of a Gene Specifies Structural Symmetry in Proteins.Darwin and Fisher meet at biotech: on the potential of computational molecular evolution in industry.Expression and characterization of a codon-optimized blood coagulation factor VIII.Codon bias and the folding dynamics of the cystic fibrosis transmembrane conductance regulator.Association between XPF polymorphisms and cancer risk: a meta-analysis.Large-scale analysis of conserved rare codon clusters suggests an involvement in co-translational molecular recognition eventsEstimating Gene Expression and Codon-Specific Translational Efficiencies, Mutation Biases, and Selection Coefficients from Genomic Data AloneSMART--Sunflower Mutant population And Reverse genetic Tool for crop improvement.Rare codons cluster.Generic algorithm to predict the speed of translational elongation: implications for protein biogenesis.Genetic identification of nascent peptides that induce ribosome stalling.Selection on synonymous codons in mammalian rhodopsins: a possible role in optimizing translational processesSynonymous ABCA3 variants do not increase risk for neonatal respiratory distress syndrome.Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapyEffect of correlated tRNA abundances on translation errors and evolution of codon usage biasThe N-terminus of GalE induces tmRNA activity in Escherichia coli.Genetic and functional analysis of the DLG4 gene encoding the post-synaptic density protein 95 in schizophrenia.Different types of secondary information in the genetic code.A critical analysis of codon optimization in human therapeutics.Engineering genes for predictable protein expressionCBDB: the codon bias database.Biophysics of protein evolution and evolutionary protein biophysicsSounds of silence: synonymous nucleotides as a key to biological regulation and complexity.Characterization of coding synonymous and non-synonymous variants in ADAMTS13 using ex vivo and in silico approachesRecombinant protein expression in Escherichia coli: advances and challengesCauses and implications of codon usage bias in RNA viruses.You're one in a googol: optimizing genes for protein expression.Human coding synonymous single nucleotide polymorphisms at ramp regions of mRNA translation.Determinants of translation efficiency and accuracy.Birth, life and death of nascent polypeptide chains.
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P2860
Synonymous mutations and ribosome stalling can lead to altered folding pathways and distinct minima.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 12 August 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Synonymous mutations and ribos ...... pathways and distinct minima.
@en
Synonymous mutations and ribos ...... pathways and distinct minima.
@nl
type
label
Synonymous mutations and ribos ...... pathways and distinct minima.
@en
Synonymous mutations and ribos ...... pathways and distinct minima.
@nl
prefLabel
Synonymous mutations and ribos ...... pathways and distinct minima.
@en
Synonymous mutations and ribos ...... pathways and distinct minima.
@nl
P2093
P2860
P1476
Synonymous mutations and ribos ...... pathways and distinct minima.
@en
P2093
Chava Kimchi-Sarfaty
Chung-Jung Tsai
Michael M Gottesman
Suresh V Ambudkar
Zuben E Sauna
P2860
P304
P356
10.1016/J.JMB.2008.08.012
P407
P577
2008-08-12T00:00:00Z