Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.
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Guidance molecules in lung cancerRegeneration of the lung: Lung stem cells and the development of lung mimicking devicesEarly events in the pathogenesis of chronic obstructive pulmonary disease. Smoking-induced reprogramming of airway epithelial basal progenitor cellsAre healthy smokers really healthy?Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary functionNotch pathway activation is essential for maintenance of stem-like cells in early tongue cancerAnalysis of the transcriptome in molecular epidemiology studiesIdentification of potential COPD genes based on multi-omics data at the functional level.Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal EpitheliumMolecular processes that drive cigarette smoke-induced epithelial cell fate of the lung.Stem cells and cell therapies in lung biology and diseases: conference report.Down-regulation of the canonical Wnt β-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD.The human airway epithelial basal cell transcriptome.Biologic phenotyping of the human small airway epithelial response to cigarette smoking.Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling.Integrative genomics of chronic obstructive pulmonary disease.A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment.Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.Transcriptional programs controlling perinatal lung maturationHigh correlation of the response of upper and lower lobe small airway epithelium to smokingNotch3-Jagged signaling controls the pool of undifferentiated airway progenitors.COPD: balancing oxidants and antioxidants.Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas.A novel autoantibody test for the detection of pre-neoplastic lung lesionsNotch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.Downregulation of notch signaling pathway in late preterm and term placentas from pregnancies complicated by preeclampsia.Genetics and genomics of chronic obstructive pulmonary diseaseMechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary diseaseThe pathogenesis of COPD and IPF: distinct horns of the same devil?Cigarette smoke induces the expression of Notch3, not Notch1, protein in lung adenocarcinoma.Human adipose-derived stem cells ameliorate cigarette smoke-induced murine myelosuppression via secretion of TSG-6.Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers.Notch-dependent differentiation of adult airway basal stem cells.Notch signaling controls the balance of ciliated and secretory cell fates in developing airwaysTrachea epithelium as a "canary" for cigarette smoking-induced biologic phenotype of the small airway epithelium.Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity.Molecular determinants of lung development.Personalized management of chronic obstructive pulmonary disease via transcriptomic profiling of the airway and lung.Airway gene expression in chronic obstructive pulmonary disease.
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P2860
Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Down-regulation of the notch p ...... obstructive pulmonary disease.
@en
Down-regulation of the notch p ...... obstructive pulmonary disease.
@nl
type
label
Down-regulation of the notch p ...... obstructive pulmonary disease.
@en
Down-regulation of the notch p ...... obstructive pulmonary disease.
@nl
prefLabel
Down-regulation of the notch p ...... obstructive pulmonary disease.
@en
Down-regulation of the notch p ...... obstructive pulmonary disease.
@nl
P2093
P2860
P1476
Down-regulation of the notch p ...... obstructive pulmonary disease.
@en
P2093
Adriana Heguy
Ann E Tilley
Ben-Gary Harvey
Neil R Hackett
Ronald G Crystal
Timothy P O'Connor
P2860
P304
P356
10.1164/RCCM.200705-795OC
P407
P577
2008-12-23T00:00:00Z