Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD.
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C9orf72's Interaction with Rab GTPases-Modulation of Membrane Traffic and AutophagyProtein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?Valproic acid induces autophagy by suppressing the Akt/mTOR pathway in human prostate cancer cells.ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling.Naringin in Ganshuang Granule suppresses activation of hepatic stellate cells for anti-fibrosis effect by inhibition of mammalian target of rapamycin.Structural and functional analysis of the GABARAP interaction motif (GIM).Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain UbiquitinationProteostasis disturbance in amyotrophic lateral sclerosis.Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder.p62 filaments capture and present ubiquitinated cargos for autophagy.Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis.Causative Genes in Amyotrophic Lateral Sclerosis and Protein Degradation Pathways: a Link to Neurodegeneration.Ageing as a risk factor for ALS/FTD.Autophagy as a common pathway in amyotrophic lateral sclerosis.Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia.Inhibition of p70 S6 kinase activity by A77 1726 induces autophagy and enhances the degradation of superoxide dismutase 1 (SOD1) protein aggregates.Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model.Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.Autophagy in Age-Associated Neurodegeneration.Amyotrophic lateral sclerosisATD: a comprehensive bioinformatics resource for deciphering the association of autophagy and diseases
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P2860
Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 May 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Defective recognition of LC3B ...... hogenic mechanism in ALS-FTLD.
@en
Defective recognition of LC3B ...... hogenic mechanism in ALS-FTLD.
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type
label
Defective recognition of LC3B ...... hogenic mechanism in ALS-FTLD.
@en
Defective recognition of LC3B ...... hogenic mechanism in ALS-FTLD.
@nl
prefLabel
Defective recognition of LC3B ...... hogenic mechanism in ALS-FTLD.
@en
Defective recognition of LC3B ...... hogenic mechanism in ALS-FTLD.
@nl
P2093
P2860
P50
P1433
P1476
Defective recognition of LC3B ...... hogenic mechanism in ALS-FTLD.
@en
P2093
Alice Goode
Barry Shaw
Daniel Scott
Jill Sollenberger
Kevin Butler
Mark S Searle
P2860
P304
P356
10.1080/15548627.2016.1170257
P577
2016-05-09T00:00:00Z