Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: role of mitochondrial reactive oxygen species.

Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: role of mitochondrial reactive oxygen species.

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http://www.wikidata.org/entity/Q37213794

Q37213794

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Role of redoximiRs in fibrogenesis Reactive oxygen species and mitochondria: A nexus of cellular homeostasis The balance of powers: Redox regulation of fibrogenic pathways in kidney injury Reactive Oxygen Species: Physiological and Physiopathological Effects on Synaptic Plasticity Oxidant Mechanisms in Renal Injury and Disease Nitro-Arachidonic Acid Prevents Angiotensin II-Induced Mitochondrial Dysfunction in a Cell Line of Kidney Proximal Tubular Cells Nitrite treatment rescues cardiac dysfunction in aged mice treated with conjugated linoleic acid.Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II Cyclic nucleotide signalling in kidney fibrosis.Mitochondrial regulation of NADPH oxidase in hindlimb unweighting rat cerebral arteries.Upstream regulators and downstream effectors of NADPH oxidases as novel therapeutic targets for diabetic kidney disease.Thioredoxin Activates MKK4-NFκB Pathway in a Redox-dependent Manner to Control Manganese Superoxide Dismutase Gene Expression in Endothelial Cells.Losartan treatment attenuates tumor-induced myocardial dysfunction Activation of AMP-activated protein kinase prevents TGF-β1-induced epithelial-mesenchymal transition and myofibroblast activation.Cystathione gamma lyase/Hydrogen Sulphide Pathway Up Regulation Enhances the Responsiveness of α1A and α1B-Adrenoreceptors in the Kidney of Rats with Left Ventricular Hypertrophy.Angiotensin II stimulates superoxide production by nitric oxide synthase in thick ascending limbs.Luminal flow induces NADPH oxidase 4 translocation to the nuclei of thick ascending limbs Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling Angiotensin converting enzyme 2/Ang-(1-7)/mas axis protects brain from ischemic injury with a tendency of age-dependence Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications Targeting of Rho kinase ameliorates impairment of diabetic endothelial function in intrarenal artery.Diabetes and Kidney Disease: Role of Oxidative Stress.2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside Promotes Expression of the Longevity Gene Klotho.Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?Redox signaling as a therapeutic target to inhibit myofibroblast activation in degenerative fibrotic disease Novel effective drugs for diabetic kidney disease? or not?Looking into a conceptual framework of ROS-miRNA-atrial fibrillation.Nox and renal disease.Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function.ShenKang injection suppresses kidney fibrosis and oxidative stress via transforming growth factor-β/Smad3 signalling pathway in vivo and in vitro.Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms.Responses to reductive stress in the cardiovascular system.The effect of angiotensin II microinjection into the bed nucleus of the stria terminalis on serum lipid peroxidation and nitric oxide metabolite levels.Mitochondrial ROS deficiency and diabetic complications: AMP[K]-lifying the adaptation to hyperglycemia.Lack of Fibronectin Extra Domain A Alternative Splicing Exacerbates Endothelial Dysfunction in Diabetes.Inhibition of 12/15-Lipoxygenase Reduces Renal Inflammation and Injury in Streptozotocin-Induced Diabetic Mice.NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance.Hierarchy of molecules in TGF-β1 signaling relevant to myofibroblast activation and renal fibrosis Increased renal oxidative stress in salt-sensitive human GRK4γ486V transgenic mice.Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells.

P2860

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P2860

Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: role of mitochondrial reactive oxygen species.

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http://www.wikidata.org/entity/Q37213794

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scientific article published on 12 August 2013

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