Common polygenic variation enhances risk prediction for Alzheimer's disease. - Wikidata - wikimedia - TriplyDB

Common polygenic variation enhances risk prediction for Alzheimer's disease.

Common polygenic variation enhances risk prediction for Alzheimer's disease.

http://www.wikidata.org/entity/Q37220545

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Towards Personalized Intervention for Alzheimer's Disease Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.Study protocol: Insight 46 - a neuroscience sub-study of the MRC National Survey of Health and Development.Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.Is bigger always better? The importance of cortical configuration with respect to cognitive ability.Multimodal Brain Imaging Reveals Structural Differences in Alzheimer's Disease Polygenic Risk Carriers: A Study in Healthy Young Adults.Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid Validating the role of the Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) and a genetic risk score in progression to cognitive impairment in a population-based cohort of older adults followed for 12 years Genetic Stratification to Identify Risk Groups for Alzheimer's Disease.PRECISION MEDICINE - The Golden Gate for Detection, Treatment and Prevention of Alzheimer's Disease.Polygenic risk score analysis of pathologically confirmed Alzheimer disease.Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.Gene discovery in amyotrophic lateral sclerosis: implications for clinical management.Polygenic risk of Alzheimer disease is associated with early- and late-life processes.Polygenic risk scores in familial Alzheimer disease.From Common to Rare Variants: The Genetic Component of Alzheimer Disease.Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain.The Correlation between Inflammatory Biomarkers and Polygenic Risk Score in Alzheimer's Disease.3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders.Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.Psychiatric polygenic risk associates with cortical morphology and functional organization in aging.Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease.Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry.No Genetic Overlap Between Circulating Iron Levels and Alzheimer's Disease.Towards precision medicine in Alzheimer's disease: deciphering genetic data to establish informative biomarkers.DNA Modifications and Alzheimer's Disease.Genetics of Alzheimer's Disease: the Importance of Polygenic and Epistatic Components.A Network of Genetic Effects on Non-Demented Cognitive Aging: Alzheimer's Genetic Risk (CLU + CR1 + PICALM) Intensifies Cognitive Aging Genetic Risk (COMT + BDNF) Selectively for APOEɛ4 Carriers.Using induced pluripotent stem cells to explore genetic and epigenetic variation associated with Alzheimer's disease.A Blood Test for Alzheimer's Disease: Progress, Challenges, and Recommendations.Dissociable influences of APOE ε4 and polygenic risk of AD dementia on amyloid and cognition.POLARIS: Polygenic LD-adjusted risk score approach for set-based analysis of GWAS data.The Role of Genetics in Advancing Precision Medicine for Alzheimer's Disease-A Narrative Review.Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci.The genetic risk of Alzheimer's disease beyond APOE ε4: systematic review of Alzheimer's genetic risk scores

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Common polygenic variation enhances risk prediction for Alzheimer's disease.

http://www.wikidata.org/entity/Q37220545

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 21 October 2015

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Common polygenic variation enhances risk prediction for Alzheimer's disease.

@en

Common polygenic variation enhances risk prediction for Alzheimer's disease.

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type

label

Common polygenic variation enhances risk prediction for Alzheimer's disease.

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Common polygenic variation enhances risk prediction for Alzheimer's disease.

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prefLabel

Common polygenic variation enhances risk prediction for Alzheimer's disease.

@en

Common polygenic variation enhances risk prediction for Alzheimer's disease.

@nl

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Common polygenic variation enhances risk prediction for Alzheimer's disease.

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Carlos Cruchaga

http://www.w3.org/2001/XMLSchema#string

Christian Bannister

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Elisa Majounie

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GERAD/PERADES

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Gerard D Schellenberg

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IGAP consortia

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John Powell

http://www.w3.org/2001/XMLSchema#string

Julie Williams

http://www.w3.org/2001/XMLSchema#string

Lesley Jones

http://www.w3.org/2001/XMLSchema#string

Maria Vronskaya

http://www.w3.org/2001/XMLSchema#string

P2860

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

The clinical use of structural MRI in Alzheimer disease

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

PLINK: a tool set for whole-genome association and population-based linkage analyses

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

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3673-3684

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scholarly article

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10.1093/BRAIN/AWV268

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Pt 12

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138

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Cornelia M. van Duijn

Jean-Charles Lambert

Philippe Amouyel

Alfredo Ramirez

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2015-10-21T00:00:00Z

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283207589

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26490334

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Alzheimer's disease

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5006219

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