The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity.
about
Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich regionDual requirement for a newly identified phosphorylation site in p70s6kIdentification of the S6 kinase activity stimulated in quiescent brine shrimp embryos upon entry to preemergence development as p70 ribosomal protein S6 kinase: isolation of Artemia franciscana p70S6k cDNA.The nuclear receptor DHR3 modulates dS6 kinase-dependent growth in DrosophilaTarget of rapamycin signalling mediates the lifespan-extending effects of dietary restriction by essential amino acid alteration.MAP4K3 is a component of the TORC1 signalling complex that modulates cell growth and viability in Drosophila melanogaster.Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.A heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo.MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila.Drosophila larvae lacking the bcl-2 gene, buffy, are sensitive to nutrient stress, maintain increased basal target of rapamycin (Tor) signaling and exhibit characteristics of altered basal energy metabolism.The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway.Role of TOR signaling in aging and related biological processes in Drosophila melanogasterRegulation of cellular growth by the Drosophila target of rapamycin dTORGenetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin.p70 S6 kinase and actin dynamics: A perspective.The role of mechanistic target of rapamycin (mTOR) complexes signaling in the immune responses.Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation.Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.Functional analysis of the PP2A subfamily of protein phosphatases in regulating Drosophila S6 kinase.Re-evaluating AKT regulation: role of TOR complex 2 in tissue growthRapamycin inhibition of baculovirus recombinant (BVr) ribosomal protein S6 kinase (S6K1) is mediated by an event other than phosphorylationCDNA cloning and characterization of S6 kinase and its effect on yolk protein gene expression in the oriental fruit fly Bactrocera dorsalis (Hendel).Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth.
P2860
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P2860
The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on October 1996
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Drosophila p70s6k homolog ...... nts and rapamycin sensitivity.
@en
The Drosophila p70s6k homolog ...... nts and rapamycin sensitivity.
@nl
type
label
The Drosophila p70s6k homolog ...... nts and rapamycin sensitivity.
@en
The Drosophila p70s6k homolog ...... nts and rapamycin sensitivity.
@nl
prefLabel
The Drosophila p70s6k homolog ...... nts and rapamycin sensitivity.
@en
The Drosophila p70s6k homolog ...... nts and rapamycin sensitivity.
@nl
P2093
P2860
P356
P1476
The Drosophila p70s6k homolog ...... nts and rapamycin sensitivity.
@en
P2093
P2860
P304
10791-10796
P356
10.1073/PNAS.93.20.10791
P407
P577
1996-10-01T00:00:00Z