Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression.
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Genetic deletion of TNFR2 augments inflammatory response and blunts satellite-cell-mediated recovery response in a hind limb ischemia model.The saponin D39 blocks dissociation of non-muscular myosin heavy chain IIA from TNF receptor 2, suppressing tissue factor expression and venous thrombosis.NMMHC IIA inhibition impedes tissue factor expression and venous thrombosis via Akt/GSK3β-NF-κB signalling pathways in the endothelium.
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Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Release of nonmuscle myosin II ...... ed for target gene expression.
@en
Release of nonmuscle myosin II ...... ed for target gene expression.
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type
label
Release of nonmuscle myosin II ...... ed for target gene expression.
@en
Release of nonmuscle myosin II ...... ed for target gene expression.
@nl
prefLabel
Release of nonmuscle myosin II ...... ed for target gene expression.
@en
Release of nonmuscle myosin II ...... ed for target gene expression.
@nl
P2093
P2860
P1433
P1476
Release of nonmuscle myosin II ...... ed for target gene expression.
@en
P2093
Jordan R Beach
Katherine Lyons
Lisa Dechert
Lori Mavrakis
Matthew Waitkus
Paul E DiCorleto
Paul L Fox
Thomas T Egelhoff
Uchechukwu I Davidson
Unni M Chandrasekharan
P2860
P356
10.1126/SCISIGNAL.2003743
P577
2013-07-16T00:00:00Z