Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.
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Taccalonolide microtubule stabilizersThe taccalonolides and paclitaxel cause distinct effects on microtubule dynamics and aster formationMechanism of microtubule stabilization by taccalonolide AJ.Cytotoxic dimeric epipolythiodiketopiperazines from the ascomycetous fungus Preussia typharumSynthetic reactions with rare taccalonolides reveal the value of C-22,23 epoxidation for microtubule stabilizing potency.Melampodium leucanthum, a source of cytotoxic sesquiterpenes with antimitotic activities.Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities.Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy.Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration.Synthesis and Evaluation of Millepachine Amino Acid Prodrugs With Enhanced Solubility as Antitumor Agents.Drosophila Ringmaker regulates microtubule stabilization and axonal extension during embryonic developmentPharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy.Taccalonolide Microtubule Stabilizers Generated Using Semisynthesis Define the Effects of Mono Acyloxy Moieties at C-7 or C-15 and Disubstitutions at C-7 and C-25.Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.
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Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Taccalonolide binding to tubul ...... y and potent in vivo activity.
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Taccalonolide binding to tubul ...... y and potent in vivo activity.
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type
label
Taccalonolide binding to tubul ...... y and potent in vivo activity.
@en
Taccalonolide binding to tubul ...... y and potent in vivo activity.
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prefLabel
Taccalonolide binding to tubul ...... y and potent in vivo activity.
@en
Taccalonolide binding to tubul ...... y and potent in vivo activity.
@nl
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Taccalonolide binding to tubul ...... ty and potent in vivo activity
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A L Risinger
C C Rohena
D C Schriemer
M J Bennett
S L Mooberry
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P304
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10.1158/0008-5472.CAN-13-1346
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2013-09-18T00:00:00Z