Decorin suppresses prostate tumor growth through inhibition of epidermal growth factor and androgen receptor pathways.
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15-lipoxygenase metabolites of docosahexaenoic acid inhibit prostate cancer cell proliferation and survivalProteoglycan form and function: A comprehensive nomenclature of proteoglycansCalcium efflux activity of plasma membrane Ca2+ ATPase-4 (PMCA4) mediates cell cycle progression in vascular smooth muscle cellsDinosaurs and ancient civilizations: reflections on the treatment of cancerAntiangiogenic mechanisms and factors in breast cancer treatmentDecorin: A Growth Factor Antagonist for Tumor Growth InhibitionPivotal role for decorin in angiogenesisInsights into the key roles of proteoglycans in breast cancer biology and translational medicineSignaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin.Decorin deficiency promotes hepatic carcinogenesisLobe-specific proteome changes in the dorsal-lateral and ventral prostate of TRAMP mice versus wild-type miceEndogenous synthesis of n-3 polyunsaturated fatty acids in Fat-1 mice is associated with increased mammary gland and liver syndecan-1.Syndecan-1-dependent suppression of PDK1/Akt/bad signaling by docosahexaenoic acid induces apoptosis in prostate cancerStromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycansDecorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft modelDecorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.Modulation of small leucine-rich proteoglycans (SLRPs) expression in the mouse uterus by estradiol and progesterone.Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling.Frequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies.The interconnectedness of cancer cell signaling.Animal models relevant to human prostate carcinogenesis underlining the critical implication of prostatic stem/progenitor cells.Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate CancerDeregulation of decorin and FHL1 are associated with esophageal squamous cell carcinoma progression and poor prognosisLocalization of decorin gene expression in normal human breast tissue and in benign and malignant tumors of the human breast.Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy.Proteoglycans in cancer biology, tumour microenvironment and angiogenesis.Dichotomy of decorin activity on the insulin-like growth factor-I systemDecorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis.Matricellular proteins as regulators of cancer metastasis to bone.Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.The War on Cancer rages on.Proteoglycans in prostate cancer.Specific changes in the expression of imprinted genes in prostate cancer--implications for cancer progression and epigenetic regulation.Recombinant production of proteoglycans and their bioactive domains.Epidermal growth factor increases LRF/Pokemon expression in human prostate cancer cells.Prostate cancer cells specifically reorganize epithelial cell-fibroblast communication through proteoglycan and junction pathways.The role of glycans in the development and progression of prostate cancer.
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P2860
Decorin suppresses prostate tumor growth through inhibition of epidermal growth factor and androgen receptor pathways.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Decorin suppresses prostate tu ...... nd androgen receptor pathways.
@en
Decorin suppresses prostate tu ...... nd androgen receptor pathways.
@nl
type
label
Decorin suppresses prostate tu ...... nd androgen receptor pathways.
@en
Decorin suppresses prostate tu ...... nd androgen receptor pathways.
@nl
prefLabel
Decorin suppresses prostate tu ...... nd androgen receptor pathways.
@en
Decorin suppresses prostate tu ...... nd androgen receptor pathways.
@nl
P2093
P2860
P356
P1433
P1476
Decorin suppresses prostate tu ...... nd androgen receptor pathways.
@en
P2093
Donna Perry
Haiguo Sun
Iris J Edwards
Isabelle M Berquin
Jiansheng Wu
Joseph T O'Flaherty
Rick T Owens
Yong Q Chen
Yunping Hu
P2860
P304
P356
10.1593/NEO.09760
P577
2009-10-01T00:00:00Z