Regulation of a transfected human class II major histocompatibility complex gene in human fibroblasts.
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Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y boxHuman X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fosA novel cysteine-rich sequence-specific DNA-binding protein interacts with the conserved X-box motif of the human major histocompatibility complex class II genes via a repeated Cys-His domain and functions as a transcriptional repressorTranscription of a subset of human class II major histocompatibility complex genes is regulated by a nucleoprotein complex that contains c-fos or an antigenically related proteinInterferon response element of the human gene 6-16A single DNA response element can confer inducibility by both alpha- and gamma-interferonsFunctional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expressionSpecific complex formation between the type II bare lymphocyte syndrome-associated transactivators CIITA and RFX5Interferons induce xanthine dehydrogenase gene expression in L929 cellsDNA binding properties of YB-1 and dbpA: binding to double-stranded, single-stranded, and abasic site containing DNAs.Active suppression of major histocompatibility complex class II gene expression during differentiation from B cells to plasma cells.Multiple regulatory regions on the 5' side of the mouse E alpha gene.Transcriptional activation of HLA-DR alpha by interferon gamma requires a trans-acting protein.Interferon-gamma-induced transcriptional activation is mediated by protein kinase CAutocrine secretion of tumor necrosis factor under the influence of interferon-gamma amplifies HLA-DR gene induction in human monocytesB-cell-specific enhancer activity of conserved upstream elements of the class II major histocompatibility complex DQB geneConserved upstream sequences of human class II major histocompatibility genes enhance expression of class II genes in wild-type but not mutant B-cell lines.B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha geneDetailed delineation of an interferon-gamma-responsive element important in human HLA-DRA gene expression in a glioblastoma multiform line.Interferon gamma response region in the promoter of the human DPA gene.The chicken ovalbumin promoter is under negative control which is relieved by steroid hormones.Repression of MHC class II gene transcription in trophoblast cells by novel single-stranded DNA binding proteins.Upstream DNA sequences required for tissue-specific expression of the HLA-DR alpha gene.Sequence-specific interactions of nuclear factors with conserved sequences of human class II major histocompatibility complex genes.The MHC class II E beta promoter: a complex arrangement of positive and negative elements determines B cell and interferon-gamma (IFN-gamma) regulated expression.Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment.Two B cell factors bind the HLA-DRA X box region and recognize different subsets of HLA class II promoters.Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeletonRegulatory factor-X binding to mutant HLA-DRA promoter sequencesAnalysis of the upstream regions governing expression of the chicken cardiac troponin T gene in embryonic cardiac and skeletal muscle cellsAllelic polymorphism in transcriptional regulatory regions of HLA-DQB genesMapping cis-acting defects in promoters of transcriptionally silent DQA2, DQB2, and DOB genes.cis-acting sequences required for class II gene regulation by interferon gamma and tumor necrosis factor alpha in a murine macrophage cell line.Structure of the mouse pore-forming protein (perforin) gene: analysis of transcription initiation site, 5' flanking sequence, and alternative splicing of 5' untranslated regions.YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes.Characterization of a cis-acting regulatory element which silences expression of the class II-A beta gene in epithelium.Two cis-DNA elements involved in myeloid-cell-specific expression and gamma interferon (IFN-gamma) activation of the human high-affinity Fc gamma receptor gene: a novel IFN regulatory mechanism.Sequence elements required for activity of a murine major histocompatibility complex class II promoter bind common and cell-type-specific nuclear factors.Transcriptional control of the invariant chain gene involves promoter and enhancer elements common to and distinct from major histocompatibility complex class II genes.Identification of cis sequences controlling efficient position-independent tissue-specific expression of human major histocompatibility complex class I genes in transgenic mice.
P2860
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P2860
Regulation of a transfected human class II major histocompatibility complex gene in human fibroblasts.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1986
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Regulation of a transfected hu ...... lex gene in human fibroblasts.
@en
Regulation of a transfected hu ...... lex gene in human fibroblasts.
@nl
type
label
Regulation of a transfected hu ...... lex gene in human fibroblasts.
@en
Regulation of a transfected hu ...... lex gene in human fibroblasts.
@nl
prefLabel
Regulation of a transfected hu ...... lex gene in human fibroblasts.
@en
Regulation of a transfected hu ...... lex gene in human fibroblasts.
@nl
P2860
P356
P1476
Regulation of a transfected hu ...... lex gene in human fibroblasts.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.23.9139
P407
P577
1986-12-01T00:00:00Z