Urea destabilizes RNA by forming stacking interactions and multiple hydrogen bonds with nucleic acid bases.
about
Single-molecule fluorescence resonance energy transfer studies of the human telomerase RNA pseudoknot: temperature-/urea-dependent folding kinetics and thermodynamics.Denaturation of RNA secondary and tertiary structure by urea: simple unfolded state models and free energy parameters account for measured m-values.Directly lighting up RNA G-quadruplexes from test tubes to living human cells.Quantifying functional group interactions that determine urea effects on nucleic acid helix formation.Translocating kilobase RNA through the Staphylococcal α-hemolysin nanopore.Molecular crowding favors reactivity of a human ribozyme under physiological ionic conditions.DIRECT-ID: An automated method to identify and quantify conformational variations--application to β2 -adrenergic GPCR.Single-molecule chemical denaturation of riboswitches.Effects of a protecting osmolyte on the ion atmosphere surrounding DNA duplexes.Introductory lecture: interpreting and predicting Hofmeister salt ion and solute effects on biopolymer and model processes using the solute partitioning modelBalancing target flexibility and target denaturation in computational fragment-based inhibitor discovery.Dispersion interactions between urea and nucleobases contribute to the destabilization of RNA by urea in aqueous solution.Probing Small Molecule Binding to Unfolded Polyprotein Based on its Elasticity and Refolding.Cation-Induced Stabilization and Denaturation of DNA Origami Nanostructures in Urea and Guanidinium Chloride.Crowders and Cosolvents-Major Contributors to the Cellular Milieu and Efficient Means to Counteract Environmental Stresses.Modulation of the Thermodynamic Signatures of an RNA Thermometer by Osmolytes and Salts.Preferential Binding of Urea to Single-Stranded DNA Structures: A Molecular Dynamics Study.MMISH: Multicolor microRNA in situ hybridization for paraffin embedded samples.
P2860
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P2860
Urea destabilizes RNA by forming stacking interactions and multiple hydrogen bonds with nucleic acid bases.
description
article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Urea destabilizes RNA by formi ...... bonds with nucleic acid bases.
@en
Urea destabilizes RNA by formi ...... bonds with nucleic acid bases.
@nl
type
label
Urea destabilizes RNA by formi ...... bonds with nucleic acid bases.
@en
Urea destabilizes RNA by formi ...... bonds with nucleic acid bases.
@nl
prefLabel
Urea destabilizes RNA by formi ...... bonds with nucleic acid bases.
@en
Urea destabilizes RNA by formi ...... bonds with nucleic acid bases.
@nl
P2093
P2860
P356
P1476
Urea destabilizes RNA by formi ...... bonds with nucleic acid bases.
@en
P2093
Alexander D Mackerell
D Thirumalai
U Deva Priyakumar
P2860
P304
17759-17761
P356
10.1021/JA905795V
P407
P577
2009-12-01T00:00:00Z