The role of body-on-a-chip devices in drug and toxicity studies.
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Modeling Barrier Tissues In Vitro: Methods, Achievements, and ChallengesBiomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniquesMicrofluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering.25th anniversary article: Rational design and applications of hydrogels in regenerative medicineMicroengineering in cardiovascular research: new developments and translational applications.From cardiac tissue engineering to heart-on-a-chip: beating challengesAdvances in Engineered Liver Models for Investigating Drug-Induced Liver InjuryOrgans-on-chips at the frontiers of drug discoveryRole of Physicochemical Properties in Nanoparticle ToxicityIntegrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective.Scaling and systems biology for integrating multiple organs-on-a-chip.New tools and new biology: recent miniaturized systems for molecular and cellular biology.Accelerating drug discovery via organs-on-chips.Microfluidics-assisted in vitro drug screening and carrier production.Advances in microfluidic materials, functions, integration, and applications.Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood VesselsCore Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage.In vitro models of tumor vessels and matrix: engineering approaches to investigate transport limitations and drug delivery in cancer.Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseasesDesign considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testingNeurovascular unit on a chip: implications for translational applications.Evaluation of the HC-04 cell line as an in vitro model for mechanistic assessment of changes in hepatic cytochrome P450 3A during adenovirus infection.Compartmentalized Culture of Perivascular Stroma and Endothelial Cells in a Microfluidic Model of the Human Endometrium.Cell Microarray Technologies for High-Throughput Cell-Based Biosensors.A functional system for high-content screening of neuromuscular junctions in vitroHow multi-organ microdevices can help foster drug developmentEthical issues in stem cell research and therapyBody-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injuryDevelopment of disposable PDMS micro cell culture analog devices with photopolymerizable hydrogel encapsulating living cells.In vitro cerebrovascular modeling in the 21st century: current and prospective technologies.Mechanistic investigation of adult myotube response to exercise and drug treatment in vitro using a multiplexed functional assay systemAllometric Scaling and Cell Ratios in Multi-Organ in vitro Models of Human Metabolism.Integrating biological vasculature into a multi-organ-chip microsystem.The relevance and potential roles of microphysiological systems in biology and medicineBiology coming full circle: joining the whole and the partsMechano-transduction: from molecules to tissuesBiomimetic tissues on a chip for drug discovery.A cost-effective fluorescence mini-microscope for biomedical applications.Physiologically relevant organs on chips.A paper-based in vitro model for on-chip investigation of the human respiratory system.
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P2860
The role of body-on-a-chip devices in drug and toxicity studies.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on August 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of body-on-a-chip devices in drug and toxicity studies.
@en
The role of body-on-a-chip devices in drug and toxicity studies.
@nl
type
label
The role of body-on-a-chip devices in drug and toxicity studies.
@en
The role of body-on-a-chip devices in drug and toxicity studies.
@nl
prefLabel
The role of body-on-a-chip devices in drug and toxicity studies.
@en
The role of body-on-a-chip devices in drug and toxicity studies.
@nl
P2093
P1476
The role of body-on-a-chip devices in drug and toxicity studies.
@en
P2093
P356
10.1146/ANNUREV-BIOENG-071910-124629
P407
P577
2011-08-01T00:00:00Z