Engineering folate-drug conjugates to target cancer: from chemistry to clinic.
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Nuclear localization of folate receptor alpha: a new role as a transcription factorTargeted drug delivery via folate receptors in recurrent ovarian cancer: a reviewCancer wars: natural products strike backFolate Receptor Targeted Delivery of siRNA and Paclitaxel to Ovarian Cancer Cells via Folate Conjugated Triblock Copolymer to Overcome TLR4 Driven Chemotherapy Resistance.Site-dependent biological activity of valinomycin analogs bearing derivatizable hydroxyl sites.Antitumor potential of conjugable valinomycins bearing hydroxyl sites: in vitro studies.Design, synthesis, and biological evaluations of tumor-targeting dual-warhead conjugates for a taxoid-camptothecin combination chemotherapy.Folate receptor-mediated enhanced and specific delivery of far-red light-activatable prodrugs of combretastatin A-4 to FR-positive tumorFolate receptor-targeted multimodality imaging of ovarian cancer in a novel syngeneic mouse modelDesign, Synthesis and Application of Fluorine-Labeled Taxoids as (19)F NMR Probes for the Metabolic Stability Assessment of Tumor-Targeted Drug Delivery Systems.Apoptosis of HeLa cells induced by a new targeting photosensitizer-based PDT via a mitochondrial pathway and ER stress.Design, synthesis and biological evaluation of a highly-potent and cancer cell selective folate-taxoid conjugate.Indocyanine green targeted micelles with improved stability for near-infrared image-guided photothermal tumor therapy.Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acidsVintafolide: a novel targeted therapy for the treatment of folate receptor expressing tumors.Antitumor Activity of Cytotoxic Cyclooxygenase-2 InhibitorsIntracellular GSH-activated galactoside photosensitizers for targeted photodynamic therapy and chemotherapy.Indium-Labeling of siRNA for Small Animal SPECT Imaging.Taxane anticancer agents: a patent perspective.Patient selection and targeted treatment in the management of platinum-resistant ovarian cancer.Cellular delivery and photochemical activation of antisense agents through a nucleobase caging strategy.Targeted treatment of folate receptor-positive platinum-resistant ovarian cancer and companion diagnostics, with specific focus on vintafolide and etarfolatide.Linker stability influences the anti-tumor activity of acetazolamide-drug conjugates for the therapy of renal cell carcinoma.Fluorescent multiblock π-conjugated polymer nanoparticles for in vivo tumor targeting.Targeting the folate receptor: diagnostic and therapeutic approaches to personalize cancer treatments.Phototoxicity of Liposomal Zn- and Al-phthalocyanine Against Cervical and Oral Squamous Cell Carcinoma Cells In VitroSynthesis and Evaluation of (99m)Tc-Labeled Dimeric Folic Acid for FR-Targeting.Pancreas-Specific Delivery of β-Cell Proliferating Small Molecules.Reversible lysine modification on proteins by using functionalized boronic acids.Design and synthesis of a multivalent fluorescent folate-calix[4]arene conjugate: cancer cell penetration and intracellular localization.Cancer nanomedicine: progress, challenges and opportunities.A bombesin-shepherdin radioconjugate designed for combined extra- and intracellular targeting.Formulation design facilitates magnetic nanoparticle delivery to diseased cells and tissuesAn immunosuppressive antibody-drug conjugate.Forming double layer-encapsulated quantum dots for bio-imaging and cell targeting.Light induced drug release from a folic acid-drug conjugate.Mitochondria-targetable carbon quantum dots for differentiating cancerous cells from normal cells.Synthesis and Superpotent Anticancer Activity of Tubulysins Carrying Non-hydrolysable N-Substituents on Tubuvaline.New mechanism for release of endosomal contents: osmotic lysis via nigericin-mediated K+/H+ exchange.A dendritic β-galactosidase-responsive folate-monomethylauristatin E conjugate.
P2860
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P2860
Engineering folate-drug conjugates to target cancer: from chemistry to clinic.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
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name
Engineering folate-drug conjugates to target cancer: from chemistry to clinic.
@en
type
label
Engineering folate-drug conjugates to target cancer: from chemistry to clinic.
@en
prefLabel
Engineering folate-drug conjugates to target cancer: from chemistry to clinic.
@en
P356
P1476
Engineering folate-drug conjugates to target cancer: from chemistry to clinic.
@en
P2093
Christopher P Leamon
Iontcho R Vlahov
P304
P356
10.1021/BC2005522
P577
2012-06-26T00:00:00Z