The role of BRCA1 in DNA double-strand repair: past and present.
about
Helicase-like transcription factor (Hltf) regulates G2/M transition, Wt1/Gata4/Hif-1a cardiac transcription networks, and collagen biogenesisA microchip platform for structural oncology applications.BRCA1 and Oxidative StressSensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damagesHuman adipose stromal cells (ASC) for the regeneration of injured cartilage display genetic stability after in vitro culture expansion.DNA repair mechanisms in cancer development and therapyβ-HPV 5 and 8 E6 disrupt homology dependent double strand break repair by attenuating BRCA1 and BRCA2 expression and foci formation.An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriersBrca1 is expressed in human microglia and is dysregulated in human and animal model of ALS.Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey.Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutationRole of the double-strand break repair pathway in the maintenance of genomic stability.Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks.Systems biology - the broader perspective.Deregulation of splicing factors and breast cancer development.Advances in PARP inhibitors for the treatment of breast cancer.MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.Novel targets for ATM-deficient malignancies.Differential Potential of Pharmacological PARP Inhibitors for Inhibiting Cell Proliferation and Inducing Apoptosis in Human Breast Cancer Cells.Downregulation of BRCA1 protein in BCR-ABL1 leukemia cells depends on stress-triggered TIAR-mediated suppression of translation.Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapyMutants TP53 p.R273H and p.R273C but not p.R273G enhance cancer cell malignancy.Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells.Put a RING on it: regulation and inhibition of RNF8 and RNF168 RING finger E3 ligases at DNA damage sites.BRCA1 promoter methylation is a marker of better response to anthracycline-based therapy in sporadic TNBC.Identification of two novel BRCA1-partner genes in the DNA double-strand break repair pathway.hsa-miR-212 modulates the radiosensitivity of glioma cells by targeting BRCA1.Genetic variants in BRIP1 (BACH1) contribute to risk of nonsyndromic cleft lip with or without cleft palate.BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.Overexpression of Ran GTPase Components Regulating Nuclear Export, but not Mitotic Spindle Assembly, Marks Chromosome Instability and Poor Prognosis in Breast Cancer.Inhibition of AKT suppresses the initiation and progression of -associated mammary tumors
P2860
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P2860
The role of BRCA1 in DNA double-strand repair: past and present.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The role of BRCA1 in DNA double-strand repair: past and present.
@en
type
label
The role of BRCA1 in DNA double-strand repair: past and present.
@en
prefLabel
The role of BRCA1 in DNA double-strand repair: past and present.
@en
P1476
The role of BRCA1 in DNA double-strand repair: past and present.
@en
P2093
Gerlinde R Van de Walle
Kevin W Caestecker
P304
P356
10.1016/J.YEXCR.2012.11.013
P407
P577
2012-11-29T00:00:00Z