In pursuit of design principles of regulatory sequences.
about
Investigating the transcriptional control of cardiovascular developmentSort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relationsDNA-dependent formation of transcription factor pairs alters their binding specificityMassively parallel cis-regulatory analysis in the mammalian central nervous systemThe appeasement of Doug: a synthetic approach to enhancer biology.Incorporating chromatin accessibility data into sequence-to-expression modelingIdentifying Cell Type-Specific Transcription Factors by Integrating ChIP-seq and eQTL Data-Application to Monocyte Gene RegulationIdentification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells.Absence of a simple code: how transcription factors read the genomeEvolving insights on how cytosine methylation affects protein-DNA binding.Quantitative modeling of transcription factor binding specificities using DNA shape.A family of transposable elements co-opted into developmental enhancers in the mouse neocortex.Temporal hierarchy of gene expression mediated by transcription factor binding affinity and activation dynamics.Understanding how cis-regulatory function is encoded in DNA sequence using massively parallel reporter assays and designed sequences.Transcriptional (ChIP-Chip) Analysis of ELF1, ETS2, RUNX1 and STAT5 in Human Abdominal Aortic AneurysmCore promoter sequence in yeast is a major determinant of expression level.Unraveling determinants of transcription factor binding outside the core binding site.A widespread role of the motif environment in transcription factor binding across diverse protein familiesPredicting the impact of promoter variability on regulatory outputsPooled ChIP-Seq Links Variation in Transcription Factor Binding to Complex Disease Risk.Basset: learning the regulatory code of the accessible genome with deep convolutional neural networksHow motif environment influences transcription factor search dynamics: Finding a needle in a haystackSequences flanking the core-binding site modulate glucocorticoid receptor structure and activity.A Simple Grammar Defines Activating and Repressing cis-Regulatory Elements in PhotoreceptorsA Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle.Unveiling DNA structural features of promoters associated with various types of TSSs in prokaryotic transcriptomes and their role in gene expression.Using synthetic bacterial enhancers to reveal a looping-based mechanism for quenching-like repression.DNA-mediated cooperativity facilitates the co-selection of cryptic enhancer sequences by SOX2 and PAX6 transcription factors.Functional organization of an Mbp enhancer exposes striking transcriptional regulatory diversity within myelinating glia."Hit-and-run": Transcription factors get caught in the act.Epistatic Interactions in the Arabinose Cis-Regulatory Element.Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis.New Repeat Polymorphism in the AKT1 Gene Predicts Striatal Dopamine D2/D3 Receptor Availability and Stimulant-Induced Dopamine Release in the Healthy Human Brain.Modeling protein-DNA binding via high-throughput in vitro technologies.Spatiotemporal regulation of enhancers during cardiogenesis.The analysis of novel distal Cebpa enhancers and silencers using a transcriptional model reveals the complex regulatory logic of hematopoietic lineage specification.On the mechanistic nature of epistasis in a canonical cis-regulatory element.Quality of TCR signaling determined by differential affinities of enhancers for the composite BATF-IRF4 transcription factor complex.Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape.GeneHancer: genome-wide integration of enhancers and target genes in GeneCards.
P2860
Q26865493-CF1D1073-668F-45E7-8FB8-51ADC15B0A0FQ27316616-7E65E70F-A667-4E7E-BB25-BC382C1E2B6FQ27702589-525A5918-428A-4DAD-8CE1-4415D623C571Q28973610-AF48C6EE-D0D5-4427-A426-022D22796FC2Q30385188-41E60485-EC8B-4780-A52C-5A708DBC22BDQ30908787-99F23DED-0CE5-451F-AFBB-7906DBFAC028Q31150872-FED15044-E22B-4A2B-8776-9064567668A0Q33882617-694273D7-0ACA-41BC-81FE-7538B1F29454Q34111752-C9654797-9322-494F-85D5-C963C2051FA6Q35003119-F3F13919-2040-4F57-921D-3C5885C2A319Q35485439-FBD4B860-864F-4209-A05A-A478FE8A7408Q35625658-83E6ADD6-CC37-4AB9-AE2A-E01EA90569C4Q35660182-56911EB2-C99C-4893-877C-71D10F5B306AQ35662980-8B273AF1-1776-42A4-9807-72B0FDA0A7EFQ35723687-7CDCEA6D-37E9-4528-A25B-180E4E4B3812Q35793473-6A184BFE-F708-4758-A767-CFE838F72286Q35793479-40224BB1-470B-4B4C-B710-9421381C03E2Q36032482-2ECFA18D-B607-46EB-BFCF-5180A8C91C4AQ36379532-F376FB7B-06A8-4BB2-A692-B115ABA24808Q36828596-49A83CC4-5DDC-499D-B4E9-FD247E6363ECQ37076984-874DCD8F-34D2-4133-9DF9-5FBB880C616AQ37255786-28CBE94D-8A4C-4309-913F-0591AB527013Q37260808-9C548AA5-8360-4773-8FFA-584A8D04101AQ37441865-A17ABCF0-DF86-4C3E-8985-688D0AF87EE9Q37590441-609C178C-5507-4896-8FDF-F9B11B34387DQ37738344-752A72D7-80E1-4B82-A7AE-DD5F87DB764EQ38257435-E43AC821-4D1B-45E1-BA8B-9E1820C081A8Q38301759-E310C8C4-F15B-40CC-BC3B-09A3A14576EEQ38441469-D33618F0-028B-4DA3-A653-2C762DD3AF51Q38502495-96A996A7-F05B-4AAC-A108-0270168677D6Q38561893-28E2290E-A91E-4ECA-99A1-EE7171401DBFQ38660921-5493BC11-7470-48B0-9C6A-E571702C898AQ38729316-D58D7B80-7720-4752-BA9C-B6B9ABBD699CQ38920592-92FA65E3-9916-435E-A206-E4EC1FB76950Q38920721-F68E4106-35CA-47F4-B92D-86B9A3CB42FCQ39945896-5AC42718-8ABD-4128-8532-BA638DB1769AQ41065481-852D1044-E013-4043-9772-C8CECE2CA13EQ41686757-01938218-933E-41A1-AE30-947BEF881039Q42122566-2FAA9446-357B-43E7-88C2-931775A62180Q42208087-9F4EC579-E0D1-4013-BE21-CC548437B5C2
P2860
In pursuit of design principles of regulatory sequences.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
In pursuit of design principles of regulatory sequences.
@en
type
label
In pursuit of design principles of regulatory sequences.
@en
prefLabel
In pursuit of design principles of regulatory sequences.
@en
P2860
P356
P1476
In pursuit of design principles of regulatory sequences.
@en
P2093
Michal Levo
P2860
P2888
P304
P356
10.1038/NRG3684
P50
P577
2014-06-10T00:00:00Z
P5875
P6179
1025954650