Scaffold Hopping Approach to a New Series of Pyridine Derivatives as Potent Inhibitors of CDK2.

about

Scaffold Hopping Approach to a New Series of Pyridine Derivatives as Potent Inhibitors of CDK2.

Item

http://www.wikidata.org/entity/Q38794658

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Scaffold Hopping Approach to a ...... as Potent Inhibitors of CDK2.

@en

type

Item

label

Scaffold Hopping Approach to a ...... as Potent Inhibitors of CDK2.

@en

prefLabel

Scaffold Hopping Approach to a ...... as Potent Inhibitors of CDK2.

@en

P1476

Scaffold Hopping Approach to a ...... as Potent Inhibitors of CDK2.

@en

P2093

Qizheng Yao

http://www.w3.org/2001/XMLSchema#string

Xiaojuan Xu

http://www.w3.org/2001/XMLSchema#string

P2860

Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2

Binding mode of the 4-anilinoquinazoline class of protein kinase inhibitor: X-ray crystallographic studies of 4-anilinoquinazolines bound to cyclin-dependent kinase 2 and p38 kinase

Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles

8-Substituted O(6)-cyclohexylmethylguanine CDK2 inhibitors: using structure-based inhibitor design to optimize an alternative binding mode

Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

Synthesis and structure-activity relationships of novel indirubin derivatives as potent anti-proliferative agents with CDK2 inhibitory activities.

To cycle or not to cycle: a critical decision in cancer.

An analysis of the binding modes of ATP-competitive CDK2 inhibitors as revealed by X-ray structures of protein-inhibitor complexes.

p16(Ink4a) overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors.

The CDK inhibitors in cancer research and therapy.

P304

224-231

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/ARDP.201500335

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

349

http://www.w3.org/2001/XMLSchema#string

P577

2016-02-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

26871934

http://www.w3.org/2001/XMLSchema#string

Scaffold Hopping Approach to a New Series of Pyridine Derivatives as Potent Inhibitors of CDK2.

about

Scaffold Hopping Approach to a New Series of Pyridine Derivatives as Potent Inhibitors of CDK2.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698