about
The role of interleukin-1 in the pathogenesis of human intervertebral disc degenerationMolecular mechanisms of biological aging in intervertebral discsDual colour FISH in paraffin wax embedded bone trephines for identification of numerical and structural chromosomal abnormalities in acute myeloid leukaemia and myelodysplasiaInflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degenerationInvestigation of intervertebral disc degeneration using multivariate FTIR spectroscopic imagingCurrent understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy.Polyphenols act synergistically with doxorubicin and etoposide in leukaemia cell lines.Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1beta and TNFalpha expression profile.Nucleus pulposus phenotypic markers to determine stem cell differentiation: fact or fiction?Matrix synthesis and degradation in human intervertebral disc degeneration.Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration.An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue.Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells.The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc.Cannabinoids: novel therapies for arthritis?Degeneration of the intervertebral disc with new approaches for treating low back pain.Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degenerationDifferential effects of polyphenols on proliferation and apoptosis in human myeloid and lymphoid leukemia cell lines.Effects of bioactive compounds from carrots (Daucus carota L.), polyacetylenes, beta-carotene and lutein on human lymphoid leukaemia cells.Bioactive chemicals from carrot (Daucus carota) juice extracts for the treatment of leukemia.Development of an in vitro model to test the efficacy of novel therapies for IVD degenerationModified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration.Cannabinoid WIN-55,212-2 mesylate inhibits interleukin-1β induced matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase expression in human chondrocytes.Glutathione is key to the synergistic enhancement of doxorubicin and etoposide by polyphenols in leukaemia cell lines.Nerves are more abundant than blood vessels in the degenerate human intervertebral disc.Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1.A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration.Altered integrin mechanotransduction in human nucleus pulposus cells derived from degenerated discs.Studies of human intervertebral disc cell function in a constrained in vitro tissue culture system.Do intervertebral discs degenerate before they herniate, or after?Bioactive actions of pomegranate fruit extracts on leukemia cell lines in vitro hold promise for new therapeutic agents for leukemia.Thermally triggered injectable hydrogel, which induces mesenchymal stem cell differentiation to nucleus pulposus cells: Potential for regeneration of the intervertebral disc.Inhibiting IL-1 signaling pathways to inhibit catabolic processes in disc degeneration.Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes.Human disc degeneration is associated with increased MMP 7 expression.Expression of receptors for putative anabolic growth factors in human intervertebral disc: implications for repair and regeneration of the disc.Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degenerationAdvancing cell therapies for intervertebral disc regeneration from the lab to the clinic: Recommendations of the ORS spine sectionLeaping the hurdles in developing regenerative treatments for the intervertebral disc from preclinical to clinicalConnective tissue growth factor expression in human intervertebral disc: implications for angiogenesis in intervertebral disc degeneration
P50
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P50
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hulumtuese
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հետազոտող
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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Christine L Le Maitre
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P106
P1153
6602415503
P21
P31
P496
0000-0003-4489-7107