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Microglia centered pathogenesis in ALS: insights in cell interconnectivityAstrocyte reactivity to unconjugated bilirubin requires TNF-α and IL-1β receptor signaling pathwaysMicroglia change from a reactive to an age-like phenotype with the time in cultureN-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicityDipeptidyl Vinyl Sulfone as a Novel Chemical Tool to Inhibit HMGB1/NLRP3-Inflammasome and Inflamma-miRs in Aβ-Mediated Microglial Inflammation.Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype.Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization.Tricellulin expression in brain endothelial and neural cells.Elevated levels of bilirubin and long-term exposure impair human brain microvascular endothelial cell integrity.Cross-talk between neurons and astrocytes in response to bilirubin: early beneficial effects.Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid.Cross-talk between neurons and astrocytes in response to bilirubin: adverse secondary impacts.Dynamics of neuron-glia interplay upon exposure to unconjugated bilirubin.Glycoursodeoxycholic acid reduces matrix metalloproteinase-9 and caspase-9 activation in a cellular model of superoxide dismutase-1 neurodegeneration.Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an Early Stage.ER stress, mitochondrial dysfunction and calpain/JNK activation are involved in oligodendrocyte precursor cell death by unconjugated bilirubin.Selective vulnerability of rat brain regions to unconjugated bilirubin.Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin.Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10.Features of bilirubin-induced reactive microglia: from phagocytosis to inflammation.Secretome from SH-SY5Y APP Swe cells trigger time-dependent CHME3 microglia activation phenotypes, ultimately leading to miR-21 exosome shuttlingGlycoursodeoxycholic Acid and Interleukin-10 Modulate the Reactivity of Rat Cortical Astrocytes to Unconjugated BilirubinCortical Neurotoxic Astrocytes with Early ALS Pathology and miR-146a Deficit Replicate Gliosis Markers of Symptomatic SOD1G93A Mouse ModelPhenotypic Effects of Wild-Type and Mutant SOD1 Expression in N9 Murine Microglia at Steady State, Inflammatory and Immunomodulatory ConditionsDevelopment of a high throughput methodology to screen cathinones' toxicological impactTargeting gliomas with triazene-based hybrids: Structure-activity relationship, mechanistic study and stability
P50
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description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Ana R Vaz
@es
Ana R Vaz
@nl
Ana R Vaz
@sl
Ana R. Vaz
@en
type
label
Ana R Vaz
@es
Ana R Vaz
@nl
Ana R Vaz
@sl
Ana R. Vaz
@en
altLabel
Ana Rita Vaz
@en
prefLabel
Ana R Vaz
@es
Ana R Vaz
@nl
Ana R Vaz
@sl
Ana R. Vaz
@en
P1053
M-5149-2013
P106
P1153
35851090700
56383998000
P21
P31
P3829
P496
0000-0002-3418-3269