about
IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNAJak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesisThe good and the bad faces of STAT1 in solid tumoursThe regulation of inflammation by interferons and their STATsIn vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesisInducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivoConditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infectionAn unusual splice defect in the mitofusin 2 gene (MFN2) is associated with degenerative axonopathy in Tyrolean Grey cattleFixed nucleotide differences on the Y chromosome indicate clear divergence between Equus przewalskii and Equus caballusCDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon responseSpecificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression.Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesisType I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infectionsThe tyrosine kinase Btk regulates the macrophage response to Listeria monocytogenes infectionTYK2 kinase activity is required for functional type I interferon responses in vivoNucleolar proteins and ultrastructure in bovine in vivo developed, in vitro produced, and parthenogenetic cleavage-stage embryos.Nucleolar protein allocation and ultrastructure in bovine embryos produced by nuclear transfer from embryonic cells.Isolation of Y chromosome-specific microsatellites in the horse and cross-species amplification in the genus Equus.A time- and dose-dependent STAT1 expression system.Mitochondrial DNA heteroplasmy in ovine fetuses and sheep cloned by somatic cell nuclear transfer.The impact of tyrosine kinase 2 (Tyk2) on the proteome of murine macrophages and their response to lipopolysaccharide (LPS).Characterization of the interferon-producing cell in mice infected with Listeria monocytogenesTranscriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes.Octamer-binding factor 6 (Oct-6/Pou3f1) is induced by interferon and contributes to dsRNA-mediated transcriptional responses.STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity.Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27Cloned transgenic farm animals produce a bispecific antibody for T cell-mediated tumor cell killing.Development of a transgenic mouse model susceptible to human coronavirus 229E.Host-cell sensors for Plasmodium activate innate immunity against liver-stage infectionCentral role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.Role of Tyk-2 in Th9 and Th17 cells in allergic asthma.PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.Composition of parental mitochondrial DNA in cloned bovine embryos.Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.Deciphering host genotype-specific impacts on the metabolic fingerprint of Listeria monocytogenes by FTIR spectroscopy.Route of Infection Determines the Impact of Type I Interferons on Innate Immunity to Listeria monocytogenesFra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expressionTrypanosomosis: potential driver of selection in African cattlePutting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias.Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Mathias Müller
@ast
Mathias Müller
@en
Mathias Müller
@es
Mathias Müller
@nl
Mathias Müller
@sl
type
label
Mathias Müller
@ast
Mathias Müller
@en
Mathias Müller
@es
Mathias Müller
@nl
Mathias Müller
@sl
prefLabel
Mathias Müller
@ast
Mathias Müller
@en
Mathias Müller
@es
Mathias Müller
@nl
Mathias Müller
@sl
P106
P1153
35604146800
56424573800
P21
P31
P496
0000-0002-7879-3552