Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors.
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Sirtuin functions and modulation: from chemistry to the clinicTargeting heat shock proteins to modulate α-synuclein toxicityOxidative stress and epigenetic regulation in ageing and age-related diseasesEx-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanismSirtuin deacylases: a molecular link between metabolism and immunityRejuvenating sirtuins: the rise of a new family of cancer drug targetsCalcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine.Using mitochondrial sirtuins as drug targets: disease implications and available compounds.Sirtuin modulators.Are sirtuins viable targets for improving healthspan and lifespan?A nitric oxide-dependent cross-talk between class I and III histone deacetylases accelerates skin repairPharmacological approaches to restore mitochondrial function.Catalysis and mechanistic insights into sirtuin activation.Role and Therapeutic Potential of the Pro-Longevity Factor FOXO and Its Regulators in Neurodegenerative Disease.A patent review of sirtuin activators: an update.Sirtuin activators and inhibitors.Can targeting SIRT-1 to treat type 2 diabetes be a good strategy? A review.Mitochondrial dysfunction in the pathophysiology of renal diseases.Sirtuin inhibitors as anticancer agents.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.Identification of tri- and tetracyclic pyrimidinediones as sirtuin inhibitors.Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol.Enaminones in a multicomponent synthesis of 4-aryldihydropyridines for potential applications in photoinduced intramolecular electron-transfer systems.Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products.SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development.DHPA-Containing Cobalt-Based Redox Metal-Organic Cyclohelicates as Enzymatic Molecular Flasks for Light-Driven H2 Production.Biophysical characterization of hit compounds for mechanism-based enzyme activation.Theoretical approaches to identify the potent scaffold for human sirtuin1 activator: Bayesian modeling and density functional theoryMulticomponent Reactions for Diverse Synthesis ofN-Substituted and NH 1,4-DihydropyridinesEfficient Synthesis of 3,5-Dicarbamoyl-1,4-dihydropyridines from Pyridinium Salts: Key Molecules in Understanding NAD(P)+/NAD(P)H Pathways
P2860
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P2860
Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Study of 1,4-dihydropyridine s ...... uin activators and inhibitors.
@en
Study of 1,4-dihydropyridine s ...... uin activators and inhibitors.
@nl
type
label
Study of 1,4-dihydropyridine s ...... uin activators and inhibitors.
@en
Study of 1,4-dihydropyridine s ...... uin activators and inhibitors.
@nl
prefLabel
Study of 1,4-dihydropyridine s ...... uin activators and inhibitors.
@en
Study of 1,4-dihydropyridine s ...... uin activators and inhibitors.
@nl
P2093
P50
P356
P1476
Study of 1,4-dihydropyridine s ...... uin activators and inhibitors.
@en
P2093
Aleksey Kazantsev
Andrea Galmozzi
Maria Tardugno
Sarah Meade
P304
P356
10.1021/JM9008289
P407
P577
2009-09-01T00:00:00Z