FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies.
about
The history of the CATH structural classification of protein domainsThe Classification and Evolution of Enzyme FunctionThe natural history of biocatalytic mechanismsIsofunctional Protein Subfamily Detection Using Data Integration and Spectral ClusteringCATH: comprehensive structural and functional annotations for genome sequences.Using CATH-Gene3D to Analyze the Sequence, Structure, and Function of Proteins.Resolving protein structure-function-binding site relationships from a binding site similarity network perspective.Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes.Protein structure based prediction of catalytic residuesAbstracting knowledge from the Protein Data Bank.Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies.The evolution of enzyme function in the isomerases.One origin for metallo-β-lactamase activity, or two? An investigation assessing a diverse set of reconstructed ancestral sequences based on a sample of phylogenetic trees.ENZYMAP: exploiting protein annotation for modeling and predicting EC number changes in UniProt/Swiss-ProtNew functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures.Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies.Functional Annotations of Paralogs: A Blessing and a CurseThe Structure-Function Linkage DatabaseEnzyme informatics.FunTree: advances in a resource for exploring and contextualising protein function evolutionCATH-Gene3D: Generation of the Resource and Its Use in Obtaining Structural and Functional Annotations for Protein Sequences.The Classification of Protein Domains.To what extent do structural changes in catalytic metal sites affect enzyme function?Large-scale mapping of bioactive peptides in structural and sequence space.The NAD Binding Domain and the Short-Chain Dehydrogenase/Reductase (SDR) SuperfamilyFunction Diversity Within Folds and Superfamilies
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P2860
FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies.
description
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name
FunTree: a resource for explor ...... defined enzyme superfamilies.
@en
FunTree: a resource for explor ...... defined enzyme superfamilies.
@nl
type
label
FunTree: a resource for explor ...... defined enzyme superfamilies.
@en
FunTree: a resource for explor ...... defined enzyme superfamilies.
@nl
prefLabel
FunTree: a resource for explor ...... defined enzyme superfamilies.
@en
FunTree: a resource for explor ...... defined enzyme superfamilies.
@nl
P2860
P50
P356
P1476
FunTree: a resource for explor ...... defined enzyme superfamilies.
@en
P2093
Alison L Cuff
P2860
P304
P356
10.1093/NAR/GKR852
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Database issue
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P577
2011-10-17T00:00:00Z