Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: the abnormal HDL phenotypes can be corrected by treatment with LCAT.

Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: the abnormal HDL phenotypes can be corrected by treatment with LCAT.

Item
http://www.wikidata.org/entity/Q40132293
Structural Insights into High Density Lipoprotein: Old Models and New FactsDouble Superhelix Model of High Density LipoproteinapoE3[K146N/R147W] acts as a dominant negative apoE form that prevents remnant clearance and inhibits the biogenesis of HDL.Activation of lecithin:cholesterol acyltransferase by HDL ApoA-I central helices.Carboxyl terminus of apolipoprotein A-I (ApoA-I) is necessary for the transport of lipid-free ApoA-I but not prelipidated ApoA-I particles through aortic endothelial cellsAlteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL.Apolipoprotein A-I exerts bactericidal activity against Yersinia enterocolitica serotype O:3High pre-beta1 HDL concentrations and low lecithin: cholesterol acyltransferase activities are strong positive risk markers for ischemic heart disease and independent of HDL-cholesterol.Discrete roles of apoA-I and apoE in the biogenesis of HDL species: lessons learned from gene transfer studies in different mouse models.Role of the hydrophobic and charged residues in the 218-226 region of apoA-I in the biogenesis of HDLSignificance of the hydrophobic residues 225-230 of apoA-I for the biogenesis of HDL.Sequence-specific apolipoprotein A-I effects on lecithin:cholesterol acyltransferase activity.
P2860

Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: the abnormal HDL phenotypes can be corrected by treatment with LCAT.

Item
http://www.wikidata.org/entity/Q40132293
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Naturally occurring and bioeng ...... rected by treatment with LCAT.
@en
type
label
Naturally occurring and bioeng ...... rected by treatment with LCAT.
@en
prefLabel
Naturally occurring and bioeng ...... rected by treatment with LCAT.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Naturally occurring and bioeng ...... rrected by treatment with LCAT
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932