Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells.
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Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and PerspectivesMolecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancerImproving treatment strategies for patients with metastatic castrate resistant prostate cancer through personalized computational modeling.Gestational Exposure to Silymarin Increases Susceptibility of BALB/c Mice Fetuses to ApoptosisProcyanidin B2 3,3(″)-di-O-gallate, a biologically active constituent of grape seed extract, induces apoptosis in human prostate cancer cells via targeting NF-κB, Stat3, and AP1 transcription factors.Effects of magnolol on UVB-induced skin cancer development in mice and its possible mechanism of actionThe role of epithelial plasticity in prostate cancer dissemination and treatment resistancePiperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer CellsSignal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Anti-cancer natural products isolated from chinese medicinal herbsFlavonoids: A versatile source of anticancer drugs.Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.Multiple regulation pathways and pivotal biological functions of STAT3 in cancer.Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats.B7-H3 associated with tumor progression and epigenetic regulatory activity in cutaneous melanoma.The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer.Targeting silibinin in the antiproliferative pathway.Signal transducer and activator of transcription 3 (STAT3): a promising target for anticancer therapy.Advances in prostate cancer chemoprevention: a translational perspective.The strategies to control prostate cancer by chemoprevention approaches.New approaches to selectively target cancer-associated matrix metalloproteinase activity.A Review: Phytochemicals Targeting JAK/STAT Signaling and IDO Expression in Cancer.Chemopreventive opportunities to control basal cell carcinoma: Current perspectives.A STAT inhibitor patent review: progress since 2011.Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment.Biological evaluation of 2-arylidene-4, 7-dimethyl indan-1-one (FXY-1): a novel Akt inhibitor with potent activity in lung cancer.Silibinin suppresses NPM-ALK, potently induces apoptosis and enhances chemosensitivity in ALK-positive anaplastic large cell lymphoma.Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells.Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals.Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF β2.STAT3 targeting by polyphenols: Novel therapeutic strategy for melanoma.Effects of AG490 and S3I-201 on regulation of the JAK/STAT3 signaling pathway in relation to angiogenesis in TRAIL-resistant prostate cancer cells in vitro.Silibinin modulates TNF-α and IFN-γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells.Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signalingFlavonoids, a prenatal prophylaxis via targeting JAK2/STAT3 signaling to oppose IL-6/MIA associated autism.Silibinin prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease via mitochondrial stabilization.Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway.Icaritin suppresses development of neuroendocrine differentiation of prostate cancer through inhibition of IL-6/STAT3 and Aurora kinase A pathways in TRAMP mice.
P2860
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P2860
Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Silibinin inhibits constitutiv ...... rostate carcinoma DU145 cells.
@en
type
label
Silibinin inhibits constitutiv ...... rostate carcinoma DU145 cells.
@en
prefLabel
Silibinin inhibits constitutiv ...... rostate carcinoma DU145 cells.
@en
P2093
P2860
P356
P1433
P1476
Silibinin inhibits constitutiv ...... rostate carcinoma DU145 cells.
@en
P2093
Alpna Tyagi
Chapla Agarwal
Manjinder Kaur
Rajesh Agarwal
P2860
P304
P356
10.1093/CARCIN/BGM042
P407
P577
2007-03-06T00:00:00Z