The balance between acetylation and deacetylation controls Smad7 stability.
about
Regulatory factor for X-box family proteins differentially interact with histone deacetylases to repress collagen alpha2(I) gene (COL1A2) expressionSmad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55Key role for ubiquitin protein modification in TGFβ signal transductionTGF-β and BMP signaling in osteoblast differentiation and bone formationMethylation of Smad6 by protein arginine N-methyltransferase 1SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylationUSP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical studyTrichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein.Dynamics of TGF-β/Smad signalingHistone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs.The molecular mechanism underlying Roberts syndrome involves loss of ESCO2 acetyltransferase activity.Ubiquitin-dependent regulation of TGFbeta signaling in cancerInhibitory SMADs: potential regulators of ovarian functionRegulation of Smad activities.Nonhistone protein acetylation as cancer therapy targets.Histone deacetylase inhibition and the regulation of cell growth with particular reference to liver pathobiology.Acetylation and deacetylation--novel factors in muscle wasting.Acetyl-L-carnitine increases mitochondrial protein acetylation in the aged rat heart.Exposure to valproic acid inhibits chondrogenesis and osteogenesis in mid-organogenesis mouse limbs.Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling.Smad7 protein induces interferon regulatory factor 1-dependent transcriptional activation of caspase 8 to restore tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosisValproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis.Epigenetic regulation of muscle phenotype and adaptation: a potential role in COPD muscle dysfunction.SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis.To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modificationsSingle-cell analysis reveals IGF-1 potentiation of inhibition of the TGF-β/Smad pathway of fibrosis in human keratocytes in vitroSuberoylanilide hydroxamic acid attenuates paraquat-induced pulmonary fibrosis by preventing Smad7 from deacetylation in rats.Intraarticular overexpression of Smad7 ameliorates experimental arthritis.Regulating the stability of TGFbeta receptors and Smads.TGF-beta signal transduction in chronic kidney diseaseRegulation of TGF-beta signalling by protein phosphatases.Physical and functional HAT/HDAC interplay regulates protein acetylation balance.Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling.Role of Smads in TGFβ signaling.Post-translational regulation of TGF-β receptor and Smad signaling.Regulation of the transforming growth factor β pathway by reversible ubiquitylation.Role of Smad7 in inflammatory bowel diseases.The growing landscape of lysine acetylation links metabolism and cell signalling.New tricks for an old fox: impact of TGFβ on the DNA damage response and genomic stability.
P2860
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P2860
The balance between acetylation and deacetylation controls Smad7 stability.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The balance between acetylation and deacetylation controls Smad7 stability.
@en
type
label
The balance between acetylation and deacetylation controls Smad7 stability.
@en
prefLabel
The balance between acetylation and deacetylation controls Smad7 stability.
@en
P2860
P356
P1476
The balance between acetylation and deacetylation controls Smad7 stability
@en
P2093
Carl-Henrik Heldin
Maria Simonsson
P2860
P304
21797-21803
P356
10.1074/JBC.M503134200
P407
P577
2005-04-13T00:00:00Z