Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice.
about
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumorsRNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signallingIncreased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanismMethylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancersUp-regulation of human secreted frizzled homolog in apoptosis and its down-regulation in breast tumorsPurification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt actionSignal transduction by the Wnt family of ligandsNegative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancerWrch-1, a novel member of the Rho gene family that is regulated by Wnt-1Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpointRetroviral insertions in the murine His-1 locus activate the expression of a novel RNA that lacks an extensive open reading frameWnt family proteins are secreted and associated with the cell surfaceInt-6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasiaReceptor and secreted targets of Wnt-1/beta-catenin signalling in mouse mammary epithelial cellsBeta-catenin: a transforming actor on many stagesDeficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic miceWnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouseWnt signaling in breast cancer: have we come full circle?PTEN deficiency: a role in mammary carcinogenesis.Tyrosine kinase signalling in breast cancer: fibroblast growth factors and their receptorsChanges in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.Mammary Development and Breast Cancer: A Wnt PerspectiveProgesterone and Overlooked Endocrine Pathways in Breast Cancer PathogenesisIdentifying and targeting tumor-initiating cells in the treatment of breast cancerCrosstalk of the Insulin-Like Growth Factor Receptor with the Wnt Signaling Pathway in Breast CancerTargeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28microRNA regulation of Wnt signaling pathways in development and diseasep53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer.Evolution of animal models in cancer vaccine developmentTGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesisMMTV-induced mammary tumorigenesis: gene discovery, progression to malignancy and cellular pathwaysErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomasMMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancerWnt pathway is involved in pleomorphic adenomas induced by overexpression of PLAG1 in transgenic miceElevated level of Wnt5a protein in localized prostate cancer tissue is associated with better outcomeRecombinant R-spondin2 and Wnt3a up- and down-regulate novel target genes in C57MG mouse mammary epithelial cellsThe Wnt co-receptor Lrp6 is required for normal mouse mammary gland developmentThe Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiationBoth canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres
P2860
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P2860
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Expression of the int-1 gene i ...... nomas in male and female mice.
@en
type
label
Expression of the int-1 gene i ...... nomas in male and female mice.
@en
prefLabel
Expression of the int-1 gene i ...... nomas in male and female mice.
@en
P2093
P1433
P1476
Expression of the int-1 gene i ...... nomas in male and female mice.
@en
P2093
Grosschedl R
Tsukamoto AS
P304
P356
10.1016/0092-8674(88)90220-6
P407
P577
1988-11-01T00:00:00Z