miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors.
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A miR-19 regulon that controls NF-κB signalingβ-Cell MicroRNAs: Small but PowerfulEpigenetics: the missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetesMicroRNAs as pharmacological targets in diabetesRole of regulatory micro RNAs in type 2 diabetes mellitus-related inflammationMicroRNAs: new insights into chronic childhood diseasesInfluence of miRNA in insulin signaling pathway and insulin resistance: micro-molecules with a major role in type-2 diabetesMicroRNA, nutrition, and cancer preventionPost-transcriptional regulation in metabolic diseasesRegulatory Roles of MicroRNAs in DiabetesEpigenetics and Cellular MetabolismmiR-24 regulates menin in the endocrine pancreasArsenic Exposure and Type 2 Diabetes: MicroRNAs as Mechanistic Links?miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.The Biochemical Cascades of the Human Pancreatic β-Cells: The Role of MicroRNAs.MicroRNA-7a regulates pancreatic β cell function.MiR-30a targets IL-1α and regulates islet functions as an inflammation buffer and response factor.miRNAs: novel regulators of autoimmunity-mediated pancreatic β-cell destruction in type 1 diabetes.Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus.Cardiovascular importance of the microRNA-23/27/24 family.MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cells.Analysis of differential miRNA expression in the duodenum of Escherichia coli F18-sensitive and -resistant weaned pigletsComparative microRNA expression profiles of cynomolgus monkeys, rat, and human reveal that mir-182 is involved in T2D pathogenic processesThe miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis.MicroRNA expression in alpha and beta cells of human pancreatic islets.Minireview: microRNA function in pancreatic β cells.Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes.Deep sequencing of cardiac microRNA-mRNA interactomes in clinical and experimental cardiomyopathy.MiR-375 promotes redifferentiation of adult human β cells expanded in vitroStem cell approaches for diabetes: towards beta cell replacement.Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA-2, IA-2β, and GAD65.DICER Inactivation Identifies Pancreatic β-Cell "Disallowed" Genes Targeted by MicroRNAs.Addressing Bias in Small RNA Library Preparation for Sequencing: A New Protocol Recovers MicroRNAs that Evade Capture by Current Methods.The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells.Organogenesis and functional genomics of the endocrine pancreasInhibition of ZEB1 expression induces redifferentiation of adult human β cells expanded in vitro.Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning.MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells.Dysregulation of Dicer1 in beta cells impairs islet architecture and glucose metabolism.A comparative analysis of high-throughput platforms for validation of a circulating microRNA signature in diabetic retinopathy.
P2860
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P2860
miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
miRNAs control insulin content ...... of transcriptional repressors.
@en
type
label
miRNAs control insulin content ...... of transcriptional repressors.
@en
prefLabel
miRNAs control insulin content ...... of transcriptional repressors.
@en
P2093
P2860
P356
P1433
P1476
miRNAs control insulin content ...... of transcriptional repressors
@en
P2093
Amitai D Mandelbaum
Eran Hornstein
Kim A Lennox
Natalia Rivkin
Sharon Kredo-Russo
Tal Melkman-Zehavi
P2860
P304
P356
10.1038/EMBOJ.2010.361
P407
P577
2011-02-01T00:00:00Z