about
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)Peripheral Adenosine A3 Receptor Activation Causes Regulated Hypothermia in Mice That Is Dependent on Central Histamine H1 Receptors.Biphasic effect of melanocortin agonists on metabolic rate and body temperatureUncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptinUDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase. Proposed enzyme for the phosphorylation of the high mannose oligosaccharide units of lysosomal enzymesLysosomal enzyme targeting. N-Acetylglucosaminylphosphotransferase selectively phosphorylates native lysosomal enzymesEffect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in miceLysosomal enzyme phosphorylation. Recognition of a protein-dependent determinant allows specific phosphorylation of oligosaccharides present on lysosomal enzymesCommon body mass index-associated variants confer risk of extreme obesity.Genetics of gene expression and its effect on diseaseDiscovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks.The chemical uncoupler 2,4-dinitrophenol (DNP) protects against diet-induced obesity and improves energy homeostasis in mice at thermoneutralityTransgenic mice lacking white fat: models for understanding human lipoatrophic diabetes.Function of the upstream hypersensitive sites of the chicken beta-globin gene cluster in mice.A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort.Two clonal cell populations (mosaicism) in a 46,XY male with mucolipidosis II (I-cell disease)--an autosomal recessive disorder.A semi-mechanistic model for the effects of a novel glucagon receptor antagonist on glucagon and the interaction between glucose, glucagon, and insulin applied to adaptive phase II design.RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individualsIntegration of body temperature into the analysis of energy expenditure in the mousePharmacogenetics of metformin response: a step in the path toward personalized medicineAnti-obesity and metabolic efficacy of the β3-adrenergic agonist, CL316243, in mice at thermoneutrality compared to 22°CSearch for an Endogenous Bombesin-Like Receptor 3 (BRS-3) Ligand Using Parabiotic MiceLeptin in the liver: a toxic or beneficial mix?Torpor in mice is induced by both leptin-dependent and -independent mechanismsA guide to analysis of mouse energy metabolism.Bombesin-like receptor 3 regulates blood pressure and heart rate via a central sympathetic mechanismFibroblasts from patients with I-cell disease and pseudo-Hurler polydystrophy are deficient in uridine 5'-diphosphate-N-acetylglucosamine: glycoprotein N-acetylglucosaminylphosphotransferase activity.The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation.FGF21 mimetic shows therapeutic promise.Regulation of body temperature and brown adipose tissue thermogenesis by bombesin receptor subtype-3.Hyperleptinemia of pregnancy associated with the appearance of a circulating form of the leptin receptor.Steps in the phosphorylation of the high mannose oligosaccharides of lysosomal enzymes.Transplantation of adipose tissue lacking leptin is unable to reverse the metabolic abnormalities associated with lipoatrophy.Hypothermia in mouse is caused by adenosine A1 and A3 receptor agonists and AMP via three distinct mechanisms.Discovery of benzodiazepine sulfonamide-based bombesin receptor subtype 3 agonists and their unusual chirality.Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.Identification of a placental enhancer for the human leptin gene.Bombesin-Like Receptor 3: Physiology of a Functional Orphan.Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men.
P50
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P50
description
hulumtues
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հետազոտող
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name
Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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Marc L. Reitman
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P1053
B-4448-2013
P106
P1153
7005693261
P21
P2798
P31
P3829
P496
0000-0002-0426-9475