Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake.
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Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesinInsulin stimulates translocation of human GLUT4 to the membrane in fat bodies of transgenic Drosophila melanogasterSites of glucose transporter-4 vesicle fusion with the plasma membrane correlate spatially with microtubulesInsulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane rufflesRegulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of α-tubulinRole of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytesIntermediate filament-associated cytolinker plectin 1c destabilizes microtubules in keratinocytesCholesterol level regulates endosome motility via Rab proteins.Identification of a distal GLUT4 trafficking event controlled by actin polymerizationKinetics of contraction-induced GLUT4 translocation in skeletal muscle fibers from living mice.Intracellular transport of insulin granules is a subordinated random walk.Live imaging of GLUT2 glucose-dependent trafficking and its inhibition in polarized epithelial cysts.Imaging of dynamic secretory vesicles in living pollen tubes of Picea meyeri using evanescent wave microscopy.Focal Adhesion Kinase contributes to insulin-induced actin reorganization into a mesh harboring Glucose transporter-4 in insulin resistant skeletal muscle cellsInsulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein.Lighting up insulin action.Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubulesIdentification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytesThe Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocationInsulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells.Linking cytoarchitecture to metabolism: sarcolemma-associated plectin affects glucose uptake by destabilizing microtubule networks in mdx myofibers.Mapping insulin/GLUT4 circuitry.Insulin stimulates actin comet tails on intracellular GLUT4-containing compartments in differentiated 3T3L1 adipocytes.Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle.Disruption of microtubules ablates the specificity of insulin signaling to GLUT4 translocation in 3T3-L1 adipocytes.Nocodazole inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes via a microtubule-independent mechanism.A pre-docking role for microtubules in insulin-stimulated glucose transporter 4 translocation.Phosphatidylinositol 4,5-bisphosphate regulates adipocyte actin dynamics and GLUT4 vesicle recycling.Microtubule-dependent transport of secretory vesicles in RBL-2H3 cells.Insulin recruits GLUT4 from distinct compartments via distinct traffic pathways with differential microtubule dependence in rat adipocytes.Altered intragenic DNA methylation of HOOK2 gene in adipose tissue from individuals with obesity and type 2 diabetes.Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways
P2860
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P2860
Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Role for the microtubule cytos ...... lin-stimulated glucose uptake.
@en
Role for the microtubule cytos ...... lin-stimulated glucose uptake.
@nl
type
label
Role for the microtubule cytos ...... lin-stimulated glucose uptake.
@en
Role for the microtubule cytos ...... lin-stimulated glucose uptake.
@nl
prefLabel
Role for the microtubule cytos ...... lin-stimulated glucose uptake.
@en
Role for the microtubule cytos ...... lin-stimulated glucose uptake.
@nl
P2093
P2860
P1433
P1476
Role for the microtubule cytos ...... lin-stimulated glucose uptake.
@en
P2093
P2860
P304
P356
10.1042/0264-6021:3520267
P407
P478
P577
2000-12-01T00:00:00Z