about
Deazaneplanocin a is a promising drug to kill multiple myeloma cells in their nicheRelevance of cyclin D1b expression and CCND1 polymorphism in the pathogenesis of multiple myeloma and mantle cell lymphoma[18F]Fludarabine-PET in a murine model of multiple myeloma.Cyclin K and cyclin D1b are oncogenic in myeloma cells.Reassessment of the murine c-fms proto-oncogene sequence.Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apoptosis by activating the unfolded protein response pathwayThe enigmatic role of cyclin D1 in multiple myeloma.Monoclonal antibodies against human factor VIII molecular neutralize antihemophilic factor and ristocetin cofactor activities.Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells.Antiestrogenic therapies in solid cancers and multiple myeloma.Fim-1, Fim-2/c-fms, and Fim-3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectivelyMultistep virus-induced leukemogenesis in vitro: description of a model specifying three steps within the myeloblastic malignant process.Estrogenic or antiestrogenic therapies for multiple myeloma?Antioestrogen-mediated cell cycle arrest and apoptosis induction in breast cancer and multiple myeloma cells.Anti-tumor necrosis factor-alpha (TNF-alpha) treatment strategies in Crohn's disease.Cyclin D1 gene activation in human myeloma cells is independent of DNA hypomethylation or histone hyperacetylation.Recurrent mutations of the exportin 1 gene (XPO1) and their impact on selective inhibitor of nuclear export compounds sensitivity in primary mediastinal B-cell lymphoma.Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells.Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes.XPO1 in B cell hematological malignancies: from recurrent somatic mutations to targeted therapy.Cyclin D1 regulates p27(Kip1) stability in B cells.Reduction of cell proliferation and potentiation of Fas-induced apoptosis by the selective kappa-opioid receptor agonist U50 488 in the multiple myeloma LP-1 cells.Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells.Ectopic expression of cyclin D1 impairs the proliferation and enhances the apoptosis of a murine lymphoid cell line.In vitro evaluation of B-CLL cells apoptotic responses to irradiation.Pharmacological delta1- and delta2-opioid receptor subtypes in the human neuroblastoma cell line SK-N-BE: no evidence for distinct molecular entities.Detection by the comet assay of apoptosis induced in lymphoid cell lines after growth factor deprivation.A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.Growth arrest and terminal differentiation of leukemic myelomonocytic cells induced through ligation of surface CD23 antigen.HIF-1α and rapamycin act as gerosuppressant in multiple myeloma cells upon genotoxic stress.Reduction of ischemic damage in NGF-transgenic mice: correlation with enhancement of antioxidant enzyme activities.Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis.Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells.A sensitive method to quantify senescent cancer cells.The targeting of the sole cyclin D1 is not adequate for mantle cell lymphoma and myeloma therapies.Upstream mediators of the Fas apoptotic transduction pathway are defective in B-chronic lymphocytic leukemia.Dysfunction of the Fas apoptotic signaling pathway in persistent polyclonal B-cell lymphocytosis.Isolation and characterization of a monoclonal antibody specific for fibrinogen and fibrin of human origin.Viral expression in two myelomonocytic cell lines obtained from long-term bone marrow culture infected with the Friend polycythemia-inducing virus (FV-P).Pure antiestrogen-induced G1-arrest in myeloma cells results from the reduced kinase activity of cyclin D3/CDK6 complexes whereas apoptosis is mediated by endoplasmic reticulum-dependent caspases.
P50
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P50
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Brigitte Sola
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Brigitte Sola
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