IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms.
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Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the familyUbiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of HomeostasisInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationStructural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICEPrimary cross-resistance to BRAFV600E-, MEK1/2- and PI3K/mTOR-specific inhibitors in BRAF-mutant melanoma cells counteracted by dual pathway blockadeA fluorescent reporter of caspase activity for live imaging.An unconventional IAP-binding motif revealed by target-assisted iterative screening (TAIS) of the BIR3-cIAP1 domain.p42MAPK-mediated phosphorylation of xEIAP/XLX in Xenopus cytostatic factor-arrested egg extracts.echinus, required for interommatidial cell sorting and cell death in the Drosophila pupal retina, encodes a protein with homology to ubiquitin-specific proteases.Analysis of inhibitor of apoptosis protein family expression during mammary gland development.The role of ubiquitylation for the control of cell death in DrosophilaThe Drosophila effector caspase Dcp-1 regulates mitochondrial dynamics and autophagic flux via SesBThe Drosophila casein kinase Iepsilon/delta Discs overgrown promotes cell survival via activation of DIAP1 expression.Host insect inhibitor-of-apoptosis SfIAP functionally replaces baculovirus IAP but is differentially regulated by Its N-terminal leader.Inhibition of the inflammatory cytokine TNF-α increases adenovirus activity in ovarian cancer via modulation of cIAP1/2 expression.Drosophila IAP antagonists form multimeric complexes to promote cell death.The role of IAP antagonist proteins in the core apoptosis pathway of the mosquito disease vector Aedes aegypti.Differential Expression Profile of Chicken Embryo Fibroblast DF-1 Cells Infected with Cell-Adapted Infectious Bursal Disease Virus.The mitochondrial death pathway: a promising therapeutic target in diseasesIAPs limit activation of RIP kinases by TNF receptor 1 during development.The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.Baculovirus caspase inhibitors P49 and P35 block virus-induced apoptosis downstream of effector caspase DrICE activation in Drosophila melanogaster cellsFlock house virus induces apoptosis by depletion of Drosophila inhibitor-of-apoptosis protein DIAP1DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cellsCaspase signalling in the absence of apoptosis drives Jnk-dependent invasion.TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in DrosophilaCasExpress reveals widespread and diverse patterns of cell survival of caspase-3 activation during development in vivo.Viral subversion of apoptotic enzymes: escape from death row.Molecularly targeted radiosensitization of human prostate cancer by modulating inhibitor of apoptosis.Inhibitor of apoptosis proteins and apoptosis.Caspase-dependent regulation of the ubiquitin-proteasome system through direct substrate targeting.Genetic characterization of two gain-of-function alleles of the effector caspase DrICE in DrosophilaThe interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila.IAP proteins as targets for drug development in oncologyX-linked inhibitor of apoptosis deficiency in the TRAMP mouse prostate cancer modelInactivation of effector caspases through nondegradative polyubiquitylation.Inhibitor of apoptosis proteins in eukaryotic evolution and development: a model of thematic conservationEnhanced cytoprotective effects of the inhibitor of apoptosis protein cellular IAP1 through stabilization with TRAF2.Osthole induces lung cancer cell apoptosis through inhibition of inhibitor of apoptosis family proteins
P2860
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P2860
IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
IAPs are functionally non-equi ...... s through distinct mechanisms.
@en
IAPs are functionally non-equi ...... s through distinct mechanisms.
@nl
type
label
IAPs are functionally non-equi ...... s through distinct mechanisms.
@en
IAPs are functionally non-equi ...... s through distinct mechanisms.
@nl
prefLabel
IAPs are functionally non-equi ...... s through distinct mechanisms.
@en
IAPs are functionally non-equi ...... s through distinct mechanisms.
@nl
P2093
P2860
P356
P1433
P1476
IAPs are functionally non-equi ...... s through distinct mechanisms.
@en
P2093
Anna Zachariou
Mark Ditzel
Rebecca Wilson
Tencho Tenev
P2860
P2888
P356
10.1038/NCB1204
P50
P577
2004-12-05T00:00:00Z