Placement of Hydroxy Moiety on Pendant of Peptidomimetic Scaffold Modulates Mu and Kappa Opioid Receptor Efficacy.

about

Placement of Hydroxy Moiety on Pendant of Peptidomimetic Scaffold Modulates Mu and Kappa Opioid Receptor Efficacy.

Item

http://www.wikidata.org/entity/Q44347928

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Placement of Hydroxy Moiety on ...... appa Opioid Receptor Efficacy.

@en

Placement of Hydroxy Moiety on ...... appa Opioid Receptor Efficacy.

@nl

type

Item

label

Placement of Hydroxy Moiety on ...... appa Opioid Receptor Efficacy.

@en

Placement of Hydroxy Moiety on ...... appa Opioid Receptor Efficacy.

@nl

prefLabel

Placement of Hydroxy Moiety on ...... appa Opioid Receptor Efficacy.

@en

Placement of Hydroxy Moiety on ...... appa Opioid Receptor Efficacy.

@nl

P1476

Placement of Hydroxy Moiety on ...... Kappa Opioid Receptor Efficacy

@en

P2093

Irina D Pogozheva

http://www.w3.org/2001/XMLSchema#string

John R Traynor

http://www.w3.org/2001/XMLSchema#string

Nicholas W Griggs

http://www.w3.org/2001/XMLSchema#string

Tyler J Trask

http://www.w3.org/2001/XMLSchema#string

P2860

Structure of the human κ-opioid receptor in complex with JDTic

Opioid ligands with mixed mu/delta opioid receptor interactions: an emerging approach to novel analgesics

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Discovery and pharmacological evaluation of a diphenethylamine derivative (HS665), a highly potent and selective κ opioid receptor agonist

Reversal of diastereofacial selectivity in hydride reductions of N-tert-butanesulfinyl imines.

Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after i.c.v. administration in mice.

Identification of the first trans-(3R,4R)- dimethyl-4-(3-hydroxyphenyl)piperidine derivative to possess highly potent and selective opioid kappa receptor antagonist activity.

Structural insights into µ-opioid receptor activation.

Homology modeling of opioid receptor-ligand complexes using experimental constraints

In vivo characterization of MMP-2200, a mixed δ/μ opioid agonist, in mice.

P304

2549-2557

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/ACSCHEMNEURO.7B00284

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Aubrie A Harland

Henry I Mosberg

P577

2017-08-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28796483

http://www.w3.org/2001/XMLSchema#string

P932

5691919

http://www.w3.org/2001/XMLSchema#string