Binding interactions of kistrin with platelet glycoprotein IIb-IIIa: analysis by site-directed mutagenesis.
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Dynamics and functional differences between dendroaspin and rhodostomin: Insights into protein scaffolds in integrin recognitionMetalloproteases Affecting Blood Coagulation, Fibrinolysis and Platelet Aggregation from Snake Venoms: Definition and Nomenclature of Interaction SitesPositional importance of Pro53 adjacent to the Arg49-Gly50-Asp51 sequence of rhodostomin in binding to integrin alphaIIbbeta3Function of disintegrin-like/cysteine-rich domains of atrolysin A. Inhibition of platelet aggregation by recombinant protein and peptide antagonists.Disulphide-bond pattern and molecular modelling of the dimeric disintegrin EMF-10, a potent and selective integrin alpha5beta1 antagonist from Eristocophis macmahoni venom.Engineering exosite peptides for complete inhibition of factor VIIa using a protease switch with substrate phage.Snake venom hemorrhagins.Effects of the RGD loop and C-terminus of rhodostomin on regulating integrin αIIbβ3 recognition.Effect of P to A mutation of the N-terminal residue adjacent to the Rgd motif on rhodostomin: importance of dynamics in integrin recognition.RGD sequence of foot-and-mouth disease virus is essential for infecting cells via the natural receptor but can be bypassed by an antibody-dependent enhancement pathwayTargeting protein-protein interactions by rational design: mimicry of protein surfacesThe disulphide bond pattern of bitistatin, a disintegrin isolated from the venom of the viper Bitis arietans.Recombinant decorsin: dynamics of the RGD recognition site.Systematic replacement of amino acid residues within an Arg-Gly-Asp-containing loop of foot-and-mouth disease virus and effect on cell recognition.Molecular cloning and expression of catrocollastatin, a snake-venom protein from Crotalus atrox (western diamondback rattlesnake) which inhibits platelet adhesion to collagen.Amino acid sequence and molecular modelling of glycoprotein IIb-IIIa and fibronectin receptor iso-antagonists from Trimeresurus elegans venomThe integrin alpha IIb beta 3 contains distinct and interacting binding sites for snake-venom RGD (Arg-Gly-Asp) proteins. Evidence that the receptor-binding characteristics of snake-venom RGD proteins are related to the amino acid environment flankiPreferential antagonism of the interactions of the integrin alpha IIb beta 3 with immobilized glycoprotein ligands by snake-venom RGD (Arg-Gly-Asp) proteins. Evidence supporting a functional role for the amino acid residues flanking the tripeptide RDetermination of the structure of two novel echistatin variants and comparison of the ability of echistatin variants to inhibit aggregation of platelets from different species.The platelet integrin alphaIIbbeta3 binds to the RGD and AGD motifs in fibrinogen.Analysis of the roles of RGD-binding integrins, alpha(4)/alpha(9) integrins, alpha(6) integrins, and CD9 in the interaction of the fertilin beta (ADAM2) disintegrin domain with the mouse egg membrane.Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin.Population Genomic Analysis of a Pitviper Reveals Microevolutionary Forces Underlying Venom Chemistry.An RGD to LDV Motif Conversion within the Disintegrin Kistrin Generates an Integrin Antagonist That Retains Potency but Exhibits Altered Receptor SpecificityRecombinant and Chimeric Disintegrins in Preclinical ResearchExpression inPichia pastoris and characterization by circular dichroism and NMR of rhodostominImportance of the structure of the RGD-containing loop in the disintegrins echistatin and eristostatin for recognition of αIIbβ3 and αvβ3 integrins
P2860
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P2860
Binding interactions of kistrin with platelet glycoprotein IIb-IIIa: analysis by site-directed mutagenesis.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
Binding interactions of kistri ...... by site-directed mutagenesis.
@en
Binding interactions of kistri ...... by site-directed mutagenesis.
@nl
type
label
Binding interactions of kistri ...... by site-directed mutagenesis.
@en
Binding interactions of kistri ...... by site-directed mutagenesis.
@nl
prefLabel
Binding interactions of kistri ...... by site-directed mutagenesis.
@en
Binding interactions of kistri ...... by site-directed mutagenesis.
@nl
P2093
P356
P1433
P1476
Binding interactions of kistri ...... by site-directed mutagenesis.
@en
P2093
P2860
P304
P356
10.1002/PROT.340150308
P407
P577
1993-03-01T00:00:00Z