about
Induction of apoptosis in human leukemia cells by grape seed extract occurs via activation of c-Jun NH2-terminal kinasePhenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathwaysRole of reactive oxygen species in arsenic-induced transformation of human lung bronchial epithelial (BEAS-2B) cellsCadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signalingAnti-apoptotic proteins and catalase-dependent apoptosis resistance in nickel chloride-transformed human lung epithelial cellsApigenin suppresses migration and invasion of transformed cells through down-regulation of C-X-C chemokine receptor 4 expressionNADPH oxidase activation is required in reactive oxygen species generation and cell transformation induced by hexavalent chromiumQuercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR- 2 regulated AKT/mTOR/P70S6K signaling pathwaysEpithelial-mesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cellsRhoA/ROCK/PTEN signaling is involved in AT-101-mediated apoptosis in human leukemia cells in vitro and in vivo.3,3'-Diindolylmethane exhibits antileukemic activity in vitro and in vivo through a Akt-dependent process.The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cellsLuteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis.Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo.Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathwayCadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells.Ethanol enhances tumor angiogenesis in vitro induced by low-dose arsenic in colon cancer cells through hypoxia-inducible factor 1 alpha pathway.Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines.Reactive oxygen species mediate arsenic induced cell transformation and tumorigenesis through Wnt/β-catenin pathway in human colorectal adenocarcinoma DLD1 cells.Modulation of Navitoclax Sensitivity by Dihydroartemisinin-Mediated MCL-1 Repression in BCR-ABL+ B-Lineage Acute Lymphoblastic Leukemia.Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors.Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Amit Budhraja
@ast
Amit Budhraja
@en
Amit Budhraja
@es
Amit Budhraja
@nl
Amit Budhraja
@sl
type
label
Amit Budhraja
@ast
Amit Budhraja
@en
Amit Budhraja
@es
Amit Budhraja
@nl
Amit Budhraja
@sl
prefLabel
Amit Budhraja
@ast
Amit Budhraja
@en
Amit Budhraja
@es
Amit Budhraja
@nl
Amit Budhraja
@sl
P106
P1153
26022768500
P31
P496
0000-0002-4216-8608