An interface of interaction between photoreceptor cGMP phosphodiesterase catalytic subunits and inhibitory gamma subunits.
about
In vivo studies of the gamma subunit of retinal cGMP-phophodiesterase with a substitution of tyrosine-84Structural requirements of the photoreceptor phosphodiesterase gamma-subunit for inhibition of rod PDE6 holoenzyme and for its activation by transducin.A truncated form of rod photoreceptor PDE6 β-subunit causes autosomal dominant congenital stationary night blindness by interfering with the inhibitory activity of the γ-subunit.Effect of the ILE86TER mutation in the γ subunit of cGMP phosphodiesterase (PDE6) on rod photoreceptor signaling.The retinal cGMP phosphodiesterase gamma-subunit - a chameleonActivation of the cAMP-specific phosphodiesterase PDE4D3 by phosphorylation. Identification and function of an inhibitory domain.Probing domain functions of chimeric PDE6alpha'/PDE5 cGMP-phosphodiesterase.Regulation of photoreceptor phosphodiesterase catalysis by its non-catalytic cGMP-binding sites.The catalytic and GAF domains of the rod cGMP phosphodiesterase (PDE6) heterodimer are regulated by distinct regions of its inhibitory gamma subunit.The gamma-subunit of the rod photoreceptor cGMP-binding cGMP-specific PDE is expressed in mouse lung.The inhibitory gamma subunit of the rod cGMP phosphodiesterase binds the catalytic subunits in an extended linear structure.
P2860
Q28347568-1D4A6404-492C-4A79-940E-53C401E6FA0BQ33717472-0911FF96-225E-40B6-9466-33AE0F1827C6Q35156268-DCB95831-92FC-40D9-B09D-DDDF7A5D10FCQ35488803-82747175-A309-45FC-9C2F-9B0C98D838C4Q37347480-4D27DE9F-D5D1-43BF-8655-64A4CCD7964AQ40944581-7CD43881-F23B-47A7-B1AC-A16009FA3C04Q41009849-4AE2487E-7813-4C65-9D4C-87221E6D943FQ42473039-CA13D366-4950-44F4-B971-B3FFF1D85E01Q43619021-F51703BA-7277-4269-A362-38C7BFF1FBD1Q47959878-553B28C7-48C2-428B-B97C-945080262A0CQ53855022-E99E484E-4A54-49C8-AD7C-B1B00E125B93
P2860
An interface of interaction between photoreceptor cGMP phosphodiesterase catalytic subunits and inhibitory gamma subunits.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
An interface of interaction be ...... and inhibitory gamma subunits.
@en
An interface of interaction be ...... and inhibitory gamma subunits.
@nl
type
label
An interface of interaction be ...... and inhibitory gamma subunits.
@en
An interface of interaction be ...... and inhibitory gamma subunits.
@nl
prefLabel
An interface of interaction be ...... and inhibitory gamma subunits.
@en
An interface of interaction be ...... and inhibitory gamma subunits.
@nl
P2860
P356
P1476
An interface of interaction be ...... and inhibitory gamma subunits
@en
P2093
M Natochin
P2860
P304
19964-19969
P356
10.1074/JBC.271.33.19964
P407
P577
1996-08-01T00:00:00Z