about
The Drosophila microtubule-associated protein mars stabilizes mitotic spindles by crosslinking microtubules through its N-terminal regionDistinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.Exit from mitosis triggers Chs2p transport from the endoplasmic reticulum to mother-daughter neck via the secretory pathway in budding yeastMars, a Drosophila protein related to vertebrate HURP, is required for the attachment of centrosomes to the mitotic spindle during syncytial nuclear divisions.The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing.Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling.Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation.The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores.Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression.Kinetics and template nucleation of self-assembled hydroxyapatite nanocrystallites by chondroitin sulfate.A minimal number of MELT repeats supports all the functions of KNL1 in chromosome segregation.The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochoresA Consensus Binding Motif for the PP4 Protein PhosphataseA dynamic charge-charge interaction modulates PP2A:B56 substrate recruitmentResponse to Raaijmakers & MedemaEfficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complexInsights into mitotic checkpoint by integrating CRISPR and RNAi
P50
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P50
description
researcher ORCID 0000-0001-7697-7203
@en
name
Gang Zhang
@ast
Gang Zhang
@en
Gang Zhang
@es
Gang Zhang
@nl
type
label
Gang Zhang
@ast
Gang Zhang
@en
Gang Zhang
@es
Gang Zhang
@nl
prefLabel
Gang Zhang
@ast
Gang Zhang
@en
Gang Zhang
@es
Gang Zhang
@nl
P106
P31
P496
0000-0001-7697-7203