Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}
about
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repressionASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category.Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutationsASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.The changing mutational landscape of acute myeloid leukemia and myelodysplastic syndrome.The HARE-HTH and associated domains: novel modules in the coordination of epigenetic DNA and protein modificationsFunctional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine.The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.Current methods of adipogenic differentiation of mesenchymal stem cellsASXL2 Regulates Glucose, Lipid, and Skeletal Homeostasis.Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice.Functional and cancer genomics of ASXL family membersDe Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype.Mutations in epigenetic regulators in myelodysplastic syndromes.Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.Role of TET2 and ASXL1 mutations in the pathogenesis of myeloproliferative neoplasms.The ASXL-BAP1 axis: new factors in myelopoiesis, cancer and epigenetics.Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.The Role of Additional Sex Combs-Like Proteins in Cancer.A systems perspective on brown adipogenesis and metabolic activation.ASXL2 promotes proliferation of breast cancer cells by linking ERα to histone methylation.NeuCode Proteomics Reveals Bap1 Regulation of Metabolism.Natural history of chronic myelomonocytic leukemia: gene sequencing identifies multiple clonal molecular abnormalities associated with rapid progression to acute myeloid leukemiaGenome-wide association of meat quality traits and tenderness in swine.CRISPR/Cas9-mediated ASXL1 mutations in U937 cells disrupt myeloid differentiation.Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis
P2860
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P2860
Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@ast
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@en
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@en-gb
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@nl
type
label
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@ast
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@en
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@en-gb
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@nl
prefLabel
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@ast
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@en
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@en-gb
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@nl
P2093
P2860
P921
P3181
P356
P1476
Additional sex comb-like (ASXL ...... tor-activated receptor {gamma}
@en
P2093
Eun-Joo Kim
Seung Kew Yoon
Soo-Jong Um
Taesun Park
Ui-Hyun Park
P2860
P304
P3181
P356
10.1074/JBC.M110.177816
P407
P577
2011-01-14T00:00:00Z