The novel Cln1(R151X) mouse model of infantile neuronal ceroid lipofuscinosis (INCL) for testing nonsense suppression therapy
about
Moving towards effective therapeutic strategies for Neuronal Ceroid LipofuscinosisA tailored mouse model of CLN2 disease: A nonsense mutant for testing personalized therapies.Mice homozygous for c.451C>T mutation in Cln1 gene recapitulate INCL phenotype.Proteomic Profiling in the Brain of CLN1 Disease Model Reveals Affected Functional Modules.Effect of Readthrough Treatment in Fibroblasts of Patients Affected by Lysosomal Diseases Caused by Premature Termination CodonsTissue-specific variation in nonsense mutant transcript level and drug-induced read-through efficiency in the Cln1(R151X) mouse model of INCLProgress toward improved therapies for inborn errors of metabolism.Targeting Nonsense Mutations in Diseases with Translational Read-Through-Inducing Drugs (TRIDs).Homozygous PPT1 Splice Donor Mutation in a Cane Corso Dog With Neuronal Ceroid LipofuscinosisCanine neuronal ceroid lipofuscinoses: Promising models for preclinical testing of therapeutic interventions.Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations.
P2860
Q26753109-C6986BCD-86D8-4470-AF65-165E7E4BB39FQ33626697-3ED37969-7781-4C19-97DD-3035E7506AEAQ34824796-74E6C6B4-C689-42B6-ADA5-58FB69F3C5E1Q35879035-414348F9-A60B-4258-94E3-7D0C7E16F5FDQ36157628-FC82CD91-33B5-4A74-A652-D40B2F413C46Q36504289-05681EF9-837C-4655-B56F-6A0D0DDBAB9AQ38601073-19A9D7D4-1805-4BBB-B6AE-A7DD3C77BEBFQ38737126-86D90CB4-4E15-40D8-A3D9-FF8AF32CB4DCQ42328379-C125F606-CA2A-4649-AE5D-785CE4E641CEQ47786937-9B82843A-1C3B-4114-845E-192A1F803C57Q48241302-11A01A19-514F-49F3-9D87-E2106280B8E3
P2860
The novel Cln1(R151X) mouse model of infantile neuronal ceroid lipofuscinosis (INCL) for testing nonsense suppression therapy
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@ast
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@en
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@nl
type
label
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@ast
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@en
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@nl
prefLabel
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@ast
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@en
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@nl
P2093
P2860
P3181
P356
P1476
The novel Cln1(R151X) mouse mo ...... g nonsense suppression therapy
@en
P2093
Attila D Kovács
David A Pearce
Jake N Miller
P2860
P304
P3181
P356
10.1093/HMG/DDU428
P407
P577
2014-09-08T00:00:00Z