Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography
about
Crystal structure of interleukin-19 defines a new subfamily of helical cytokinesHigh Resolution NMR-based Model for the Structure of a scFv-IL-1 Complex: POTENTIAL FOR NMR AS A KEY TOOL IN THERAPEUTIC ANTIBODY DESIGN AND DEVELOPMENTCrystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1Design and analysis of rhesus cytomegalovirus IL-10 mutants as a model for novel vaccines against human cytomegalovirusStructural analysis of cytokines comprising the IL-10 familyIdentification and characterization of a +1 frameshift observed during the expression of Epstein-Barr virus IL-10 in Escherichia coli.An allosteric antibody to the leptin receptor reduces body weight and reverses the diabetic phenotype in the Lep(ob) /Lep(ob) mouse.Cytokine-receptor interactions as drug targets.Structural basis of the broadly neutralizing anti-interferon-α antibody rontalizumab.A fully human, allosteric monoclonal antibody that activates the insulin receptor and improves glycemic control.Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex.
P2860
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P2860
Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@ast
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@en
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@nl
type
label
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@ast
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@en
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@nl
prefLabel
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@ast
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@en
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@nl
P2093
P1433
P1476
Noncompetitive antibody neutra ...... ring and x-ray crystallography
@en
P2093
Brandi C Jones
Kristopher Josephson
Leigh J Walter
Mark R Walter
Ruth DiGiacomo
Stephen R Indelicato
P356
10.1016/S0969-2126(02)00791-8
P577
2002-07-01T00:00:00Z