Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy
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Avian Influenza Viruses, Inflammation, and CD8(+) T Cell ImmunityProtective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation ThresholdPreemptive priming readily overcomes structure-based mechanisms of virus escapeAcute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptidesLack of heterologous cross-reactivity towards HLA-A*02:01 restricted viral epitopes is underpinned by distinct αβT cell receptor signaturesProspects for an influenza vaccine that induces cross-protective cytotoxic T lymphocytes.Immunity to seasonal and pandemic influenza A virusesConsequences of suboptimal priming are apparent for low-avidity T-cell responses.Cold-adapted influenza and recombinant adenovirus vaccines induce cross-protective immunity against pH1N1 challenge in mice.Subsisting H1N1 influenza memory responses are insufficient to protect from pandemic H1N1 influenza challenge in C57BL/6 mice.Multiple distinct forms of CD8+ T cell cross-reactivity and specificities revealed after 2009 H1N1 influenza A virus infection in mice.T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection.Nondominant CD8 T cells are active players in the vaccine-induced antitumor immune response.Variable epitope library carrying heavily mutated survivin-derived CTL epitope variants as a new class of efficient vaccine immunogen tested in a mouse model of breast cancer.CD8+ TCR Bias and Immunodominance in HIV-1 Infection.Negative selection and peptide chemistry determine the size of naive foreign peptide-MHC class II-specific CD4+ T cell populationsMolecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination.Influenza reverse genetics: dissecting immunity and pathogenesis.A flexible docking approach for prediction of T cell receptor-peptide-MHC complexes.Co-expression of HLA-B7 and HLA-B27 alleles is associated with B7-restricted immunodominant responses following influenza infection.Epitope specificity and relative clonal abundance do not affect CD8 differentiation patterns during lymphocytic choriomeningitis virus infectionFixing an irrelevant TCR alpha chain reveals the importance of TCR beta diversity for optimal TCR alpha beta pairing and function of virus-specific CD8+ T cells.Memory precursor phenotype of CD8+ T cells reflects early antigenic experience rather than memory numbers in a model of localized acute influenza infection.Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.Thinking About Broadly Cross-Reactive Vaccines
P2860
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P2860
Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Complete modification of TCR s ...... cell immunodominance hierarchy
@ast
Complete modification of TCR s ...... cell immunodominance hierarchy
@en
Complete modification of TCR s ...... cell immunodominance hierarchy
@nl
type
label
Complete modification of TCR s ...... cell immunodominance hierarchy
@ast
Complete modification of TCR s ...... cell immunodominance hierarchy
@en
Complete modification of TCR s ...... cell immunodominance hierarchy
@nl
prefLabel
Complete modification of TCR s ...... cell immunodominance hierarchy
@ast
Complete modification of TCR s ...... cell immunodominance hierarchy
@en
Complete modification of TCR s ...... cell immunodominance hierarchy
@nl
P2860
P50
P356
P1476
Complete modification of TCR s ...... cell immunodominance hierarchy
@en
P2093
Lauren A Hatton
P2860
P304
P356
10.1073/PNAS.0810274105
P407
P50
P577
2008-12-09T00:00:00Z