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Subunit architecture and functional modular rearrangements of the transcriptional mediator complexZooming in on Transcription PreinitiationThe Mediator complex: a central integrator of transcriptionStructure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase IIInteraction of the Mediator Head Module with RNA Polymerase IIStructure of the Mediator head moduleCrystal structure of a claudin provides insight into the architecture of tight junctionsArchitecture of the RNA polymerase II-Mediator core initiation complexStructure of a Complete Mediator-RNA Polymerase II Pre-Initiation ComplexSrb5/Med18-mediated termination of transcription is dependent on gene loopingA conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.The Mediator complex and transcription regulationDisordered proteinaceous machinesA link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31.MultiBac complexomics.Structural insights into transcription initiation by RNA polymerase II.Functional studies of the yeast med5, med15 and med16 mediator tail subunits.Redefining the modular organization of the core Mediator complexMed5(Nut1) and Med17(Srb4) are direct targets of mediator histone H4 tail interactionsMC EMiNEM maps the interaction landscape of the MediatorMolecular architecture of the yeast Mediator complex.Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit.Mediator directs co-transcriptional heterochromatin assembly by RNA interference-dependent and -independent pathways.Novel role for mediator complex subunit Srb5/Med18 in termination of transcription.Evolution of disorder in Mediator complex and its functional relevanceExpression and purification of functional human glycogen synthase-1 (hGYS1) in insect cellsRole for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6α.The head module of Mediator directs activation of preloaded RNAPII in vivo.The Mediator complex and transcription elongation.Mechanisms of Mediator complex action in transcriptional activation.Development of an in silico method for the identification of subcomplexes involved in the biogenesis of multiprotein complexes in Saccharomyces cerevisiaeThe Structural Basis of Transcription: 10 Years After the Nobel Prize in Chemistry.Mediator binding to UASs is broadly uncoupled from transcription and cooperative with TFIID recruitment to promoters.Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C).Mediator can regulate mitotic entry and direct periodic transcription in fission yeast.Small molecule probes to target the human Mediator complex.The complex structure and function of Mediator.Core Mediator structure at 3.4 Å extends model of transcription initiation complex.Mediator structure and rearrangements required for holoenzyme formation.Model of the Mediator middle module based on protein cross-linking.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Architecture of the Mediator head module
@ast
Architecture of the Mediator head module
@en
Architecture of the Mediator head module
@nl
type
label
Architecture of the Mediator head module
@ast
Architecture of the Mediator head module
@en
Architecture of the Mediator head module
@nl
prefLabel
Architecture of the Mediator head module
@ast
Architecture of the Mediator head module
@en
Architecture of the Mediator head module
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Architecture of the Mediator head module
@en
P2093
Francesco Cardelli
Francisco J Asturias
Guillermo Calero
Guy Lorch Kornberg
Kentaro Yamada
Kuang-Lei Tsai
Yuichiro Takagi
P2860
P2888
P3181
P356
10.1038/NATURE10162
P407
P577
2011-07-03T00:00:00Z
P5875
P6179
1022282330