Refined X-ray crystallographic structure of the poliovirus 3C gene product
about
Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPgStimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDproRoles of the Picornaviral 3C Proteinase in the Viral Life Cycle and Host CellsMultiple enzymatic activities associated with recombinant NS3 protein of hepatitis C virusStructure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypesStructure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain.Structural basis for the substrate specificity of tobacco etch virus proteaseCrystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA PolymeraseA Structural Study of Norovirus 3C Protease Specificity: Binding of a Designed Active Site-Directed Peptide InhibitorEnterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug DesignCrystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important ResiduesStructural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 933C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against PicornavirusesStructure of a Murine Norovirus NS6 Protease-Product Complex Revealed by Adventitious CrystallisationStructures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivirInhibition of Enterovirus 71 replication by 7-hydroxyflavone and diisopropyl-flavon7-yl PhosphateFunctional binding of hexanucleotides to 3C protease of hepatitis A virus.Characterization of Bafinivirus main protease autoprocessing activities.Characterization of a torovirus main proteinaseEnterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylationRupintrivir is a promising candidate for treating severe cases of Enterovirus-71 infection.Structural aspects of activation pathways of aspartic protease zymogens and viral 3C protease precursorsA norovirus protease structure provides insights into active and substrate binding site integrityProduction of active mammalian and viral proteases in bacterial expression systems.Identification of active-site amino acid residues in the Chiba virus 3C-like proteaseComparative genomic analysis of coxsackievirus A6 strains of different clinical disease entities.Structure of the catalytic domain of the hepatitis C virus NS2-3 protease.X-ray crystallographic structure of the Norwalk virus protease at 1.5-A resolution.Benserazide, the first allosteric inhibitor of Coxsackievirus B3 3C protease.Calicivirus 3C-like proteinase inhibits cellular translation by cleavage of poly(A)-binding protein.Human cytomegalovirus UL84 interacts with an RNA stem-loop sequence found within the RNA/DNA hybrid region of oriLyt.Highly conserved configuration of catalytic amino acid residues among calicivirus-encoded proteases.Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication.Structural basis for specific recognition of substrates by sapovirus protease.Picornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex.The peptidases from fungi and viruses.Viral precursor protein P3 and its processed products perform discrete and essential functions in the poliovirus RNA replication complex.Long-Range Communication between Different Functional Sites in the Picornaviral 3C Protein.Regulation of poliovirus 3C protease by the 2C polypeptideStructural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
P2860
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P2860
Refined X-ray crystallographic structure of the poliovirus 3C gene product
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@ast
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@en
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@nl
type
label
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@ast
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@en
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@nl
prefLabel
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@ast
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@en
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@nl
P2093
P3181
P356
P1476
Refined X-ray crystallographic structure of the poliovirus 3C gene product
@en
P2093
P304
P3181
P356
10.1006/JMBI.1997.1306
P407
P577
1997-11-14T00:00:00Z