Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
about
Regulation and localization of the Bloom syndrome protein in response to DNA damageColocalization, physical, and functional interaction between Werner and Bloom syndrome proteinsBLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrityMPS1-dependent mitotic BLM phosphorylation is important for chromosome stabilityThe RecQ DNA helicases in DNA repairRMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stabilityBLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasomeThe Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase deltaTelomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicaseThe C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stabilityFunctions of Ubiquitin and SUMO in DNA Replication and Replication StressFunctional interaction of p53 and BLM DNA helicase in apoptosisFunctional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATMPotential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51The broken genome: genetic and pharmacologic approaches to breaking DNAAssociation of BLM and BRCA1 during Telomere Maintenance in ALT CellsUnwinding protein complexes in ALTernative telomere maintenance.Selective cleavage of BLM, the bloom syndrome protein, during apoptotic cell death.RecQ helicases: guardian angels of the DNA replication fork.Regulation of BLM Nucleolar LocalizationThe role of post-translational modifications in fine-tuning BLM helicase function during DNA repairWerner protein protects nonproliferating cells from oxidative DNA damageSgs1 truncations induce genome rearrangements but suppress detrimental effects of BLM overexpression in Saccharomyces cerevisiae.The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication.RecQ helicases: suppressors of tumorigenesis and premature aging.DNA end resection is needed for the repair of complex lesions in G1-phase human cells.DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1.Structure and function of RecQ DNA helicases.Protein degradation pathways regulate the functions of helicases in the DNA damage response and maintenance of genomic stabilityThe human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability.The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structuresBloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrestAccumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis.Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks.hSSB1 associates with and promotes stability of the BLM helicaseNon-Bloom syndrome-associated partial and total loss-of-function variants of BLM helicase.The BLM dissolvasome in DNA replication and repair.Monopolar spindle 1 (MPS1) protein-dependent phosphorylation of RecQ-mediated genome instability protein 2 (RMI2) at serine 112 is essential for BLM-Topo III α-RMI1-RMI2 (BTR) protein complex function upon spindle assembly checkpoint (SAC) activatioPossible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processingBloom's Syndrome: Clinical Spectrum, Molecular Pathogenesis, and Cancer Predisposition.
P2860
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P2860
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@ast
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@en
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@nl
type
label
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@ast
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@en
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@nl
prefLabel
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@ast
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@en
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@nl
P2093
P2860
P3181
P356
P1433
P1476
Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/SJ.ONC.1203595
P407
P577
2000-05-01T00:00:00Z
P5875
P6179
1019516625