Identification of an RNA binding specificity for the potential splicing factor TLS
about
Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinasesInduced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcriptionTLS inhibits RNA polymerase III transcriptionRoles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulationRGG-boxes of the EWS oncoprotein repress a range of transcriptional activation domainsFinding signals that regulate alternative splicing in the post-genomic eraMechanisms of FUS mutations in familial amyotrophic lateral sclerosisFUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysisThe function of RNA-binding proteins at the synapse: implications for neurodegenerationEarly lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif.The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequencesMutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosisDomain architectures and characterization of an RNA-binding protein, TLSEWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functionsRNA seeds higher-order assembly of FUS protein.FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.Nucleic acid-binding specificity of human FUS protein.Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasmGene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions.Having it both ways: transcription factors that bind DNA and RNA.Long noncoding RNA SchLAH suppresses metastasis of hepatocellular carcinoma through interacting with fused in sarcoma.The TET family of proteins: functions and roles in disease.High-throughput binding analysis determines the binding specificity of ASF/SF2 on alternatively spliced human pre-mRNAs.PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation.Functions of FUS/TLS from DNA repair to stress response: implications for ALS.Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granulesp54(nrb) associates with the 5' splice site within large transcription/splicing complexes.Knockdown of the Drosophila fused in sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches.Nuclear localization sequence of FUS and induction of stress granules by ALS mutants.Viral oncogenes, noncoding RNAs, and RNA splicing in human tumor virusesProtein composition of human prespliceosomes isolated by a tobramycin affinity-selection method.Activity-dependent FUS dysregulation disrupts synaptic homeostasisRegulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expressionA biophysical model for identifying splicing regulatory elements and their interactions.RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins.ALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation.Antisense RNA controls LRP1 Sense transcript expression through interaction with a chromatin-associated protein, HMGB2FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factorsTLS/FUS (translocated in liposarcoma/fused in sarcoma) regulates target gene transcription via single-stranded DNA response elementsfus/TLS orchestrates splicing of developmental regulators during gastrulation.
P2860
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P2860
Identification of an RNA binding specificity for the potential splicing factor TLS
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Identification of an RNA binding specificity for the potential splicing factor TLS
@ast
Identification of an RNA binding specificity for the potential splicing factor TLS
@en
Identification of an RNA binding specificity for the potential splicing factor TLS
@nl
type
label
Identification of an RNA binding specificity for the potential splicing factor TLS
@ast
Identification of an RNA binding specificity for the potential splicing factor TLS
@en
Identification of an RNA binding specificity for the potential splicing factor TLS
@nl
prefLabel
Identification of an RNA binding specificity for the potential splicing factor TLS
@ast
Identification of an RNA binding specificity for the potential splicing factor TLS
@en
Identification of an RNA binding specificity for the potential splicing factor TLS
@nl
P2093
P2860
P3181
P356
P1476
Identification of an RNA binding specificity for the potential splicing factor TLS
@en
P2093
F Moreau-Gachelin
P2860
P304
P3181
P356
10.1074/JBC.M008304200
P407
P577
2001-03-02T00:00:00Z