The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation
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Exposure in vivo to silica or lipopolysaccharide produces transient or sustained upregulation, respectively, of PYPAF7 and MEFV genes in bronchoalveolar lavage cells in ratsMutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndromePYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa BChronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytesThe PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulationEvaluation of Nod-like receptor (NLR) effector domain interactionsDe novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseasesThe PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathwaysThe CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signalsCARD games in apoptosis and immunityCaspases: pharmacological manipulation of cell deathA comprehensive manually curated protein-protein interaction database for the Death Domain superfamilyHorror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragmentThe PYRIN domain: a member of the death domain-fold superfamilyInflammasomes: too big to missPyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathwayUpdate on Pyrin Functions and Mechanisms of Familial Mediterranean FeverA clear and present danger: inflammasomes DAMPing down disorders of pregnancyNLRC5: a newly discovered MHC class I transactivator (CITA)Structural and Functional Analysis of the NLRP4 Pyrin DomainThe NLRP12 Pyrin Domain: Structure, Dynamics, and Functional InsightsStructure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome AssemblyNALPs: a novel protein family involved in inflammationInteraction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosisRequirement of IFI16 for the maximal activation of p53 induced by ionizing radiationActivation and assembly of the inflammasomes through conserved protein domain familiesThe PYRIN domain in signal transductionInhibiting the inflammasome: one domain at a timeNalp1b controls mouse macrophage susceptibility to anthrax lethal toxinComplex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation1Novel MEFV transcripts in Familial Mediterranean fever patients and controls.The death domain superfamily in intracellular signaling of apoptosis and inflammation.Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.Increased frequency of Mediterranean fever gene variants in multiple myeloma.Nlrp2, a maternal effect gene required for early embryonic development in the mouseFunctional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.Nod2: a key regulator linking microbiota to intestinal mucosal immunity.Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses.The NOD: a signaling module that regulates apoptosis and host defense against pathogens.
P2860
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P2860
The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The pyrin domain: a possible m ...... in apoptosis and inflammation
@ast
The pyrin domain: a possible m ...... in apoptosis and inflammation
@en
The pyrin domain: a possible m ...... in apoptosis and inflammation
@nl
type
label
The pyrin domain: a possible m ...... in apoptosis and inflammation
@ast
The pyrin domain: a possible m ...... in apoptosis and inflammation
@en
The pyrin domain: a possible m ...... in apoptosis and inflammation
@nl
prefLabel
The pyrin domain: a possible m ...... in apoptosis and inflammation
@ast
The pyrin domain: a possible m ...... in apoptosis and inflammation
@en
The pyrin domain: a possible m ...... in apoptosis and inflammation
@nl
P3181
P1433
P1476
The pyrin domain: a possible m ...... in apoptosis and inflammation
@en
P2093
P304
P3181
P356
10.1016/S0960-9822(01)00056-2
P407
P50
P577
2001-02-20T00:00:00Z