Domain architectures and characterization of an RNA-binding protein, TLS
about
Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinasesFUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitmentTLS inhibits RNA polymerase III transcriptionMechanisms of FUS mutations in familial amyotrophic lateral sclerosisFUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysisFunctions of heterogeneous nuclear ribonucleoproteins in stem cell potency and differentiationThe function of RNA-binding proteins at the synapse: implications for neurodegenerationEarly lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif.The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequencesThe neurogenetics of alternative splicingUse of (113)Cd NMR to probe the native metal binding sites in metalloproteins: an overviewIntrinsic disorder in proteins involved in amyotrophic lateral sclerosis.FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.Nucleic acid-binding specificity of human FUS protein.Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia ContinuumThe TET family of proteins: functions and roles in disease.De novo truncating FUS gene mutation as a cause of sporadic amyotrophic lateral sclerosis.Functions of FUS/TLS from DNA repair to stress response: implications for ALS.Knockdown of the Drosophila fused in sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches.Activity-dependent FUS dysregulation disrupts synaptic homeostasisThe RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damageA network of RNA and protein interactions in Fronto Temporal Dementia.Structural delineation of stem-loop RNA binding by human TAF15 protein.The RRM domain of human fused in sarcoma protein reveals a non-canonical nucleic acid binding site.RNA processing defects associated with diseases of the motor neuronFUS/TLS forms cytoplasmic aggregates, inhibits cell growth and interacts with TDP-43 in a yeast model of amyotrophic lateral sclerosis.Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutantsAmyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics.RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond.NKAP is a novel RS-related protein that interacts with RNA and RNA binding proteins.Folding of the RNA recognition motif (RRM) domains of the amyotrophic lateral sclerosis (ALS)-linked protein TDP-43 reveals an intermediate stateTDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration.The role of RNA processing in the pathogenesis of motor neuron degeneration.TDP-43 and FUS/TLS: sending a complex message about messenger RNA in amyotrophic lateral sclerosis?RNA-binding proteins involved in RNA localization and their implications in neuronal diseases.Stress granules in neurodegeneration--lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma.Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease.RNA-binding proteins in neurological diseases.The role of FUS gene variants in neurodegenerative diseases.RNA binding proteins: a common denominator of neuronal function and dysfunction.
P2860
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P2860
Domain architectures and characterization of an RNA-binding protein, TLS
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Domain architectures and characterization of an RNA-binding protein, TLS
@ast
Domain architectures and characterization of an RNA-binding protein, TLS
@en
Domain architectures and characterization of an RNA-binding protein, TLS
@nl
type
label
Domain architectures and characterization of an RNA-binding protein, TLS
@ast
Domain architectures and characterization of an RNA-binding protein, TLS
@en
Domain architectures and characterization of an RNA-binding protein, TLS
@nl
prefLabel
Domain architectures and characterization of an RNA-binding protein, TLS
@ast
Domain architectures and characterization of an RNA-binding protein, TLS
@en
Domain architectures and characterization of an RNA-binding protein, TLS
@nl
P2093
P2860
P3181
P356
P1476
Domain architectures and characterization of an RNA-binding protein, TLS
@en
P2093
Eugene H Morita
Kosuke Morikawa
Mika Okumura
Nobuyuki Kasai
Ritsuko Fujii
Shin-ichi Tate
Takanori Muto
Takashi S Kodama
Toru Takumi
P2860
P304
44834-44840
P3181
P356
10.1074/JBC.M408552200
P407
P50
P577
2004-08-06T00:00:00Z