Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C
about
Making ends meet: repairing breaks in bacterial DNA by non-homologous end-joiningRibonucleotides in bacterial DNAThe cell pole: the site of cross talk between the DNA uptake and genetic recombination machineryStructural basis for nick recognition by a minimal pluripotent DNA ligaseStructure of a NHEJ polymerase-mediated DNA synaptic complexMolecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA PolymeraseXRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gapsThe mechanism of human nonhomologous DNA end joiningMycobacterial UvrD1 is a Ku-dependent DNA helicase that plays a role in multiple DNA repair events, including double-strand break repairThe minimal Bacillus subtilis nonhomologous end joining repair machineryGap filling activities of Pseudomonas DNA ligase D (LigD) polymerase and functional interactions of LigD with the DNA end-binding Ku proteinNovel 3'-ribonuclease and 3'-phosphatase activities of the bacterial non-homologous end-joining protein, DNA ligase DA Sir2-like protein participates in mycobacterial NHEJBiochemical and Structural Characterisation of DNA Ligases from Bacteria and ArchaeaGenome analysis of DNA repair genes in the alpha proteobacterium Caulobacter crescentus.AdnAB: a new DSB-resecting motor-nuclease from mycobacteria.Characterization of the mycobacterial AdnAB DNA motor provides insights into the evolution of bacterial motor-nuclease machinesHighly precise and developmentally programmed genome assembly in Paramecium requires ligase IV-dependent end joiningCatalytic and non-catalytic roles for the mono-ADP-ribosyltransferase Arr in the mycobacterial DNA damage response.Deficiency of double-strand DNA break repair does not impair Mycobacterium tuberculosis virulence in multiple animal models of infection.Characterization of the roles of the catalytic domains of Mycobacterium tuberculosis ligase D in Ku-dependent error-prone DNA end joiningMycobacteria exploit three genetically distinct DNA double-strand break repair pathwaysCharacterization of three mycobacterial DinB (DNA polymerase IV) paralogs highlights DinB2 as naturally adept at ribonucleotide incorporation.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.Either non-homologous ends joining or homologous recombination is required to repair double-strand breaks in the genome of macrophage-internalized Mycobacterium tuberculosisAtomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase DPrimase-polymerases are a functionally diverse superfamily of replication and repair enzymes.Direct and inverted repeats elicit genetic instability by both exploiting and eluding DNA double-strand break repair systems in mycobacteria.Identification of a chemical that inhibits the mycobacterial UvrABC complex in nucleotide excision repairTuberculosis chemotherapy: the influence of bacillary stress and damage response pathways on drug efficacy.Biochemical Characterization of Mycobacterium smegmatis RnhC (MSMEG_4305), a Bifunctional Enzyme Composed of Autonomous N-Terminal Type I RNase H and C-Terminal Acid Phosphatase Domains.Ku heterodimer-independent end joining in Trypanosoma brucei cell extracts relies upon sequence microhomology.DNA repair and genome maintenance in Bacillus subtilis.The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA endsC-terminal low-complexity sequence repeats of Mycobacterium smegmatis Ku modulate DNA bindingA dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing.Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858).Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates.C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repairMechanistic flexibility as a conserved theme across 3 billion years of nonhomologous DNA end-joining.
P2860
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P2860
Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C
description
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im April 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/04/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/04/01)
@nl
наукова стаття, опублікована у квітні 2005
@uk
مقالة علمية (نشرت في أبريل 2005)
@ar
name
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@ast
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@en
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@nl
type
label
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@ast
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@en
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@nl
prefLabel
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@ast
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@en
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@nl
P2093
P2860
P3181
P356
P1476
Mechanism of nonhomologous end ...... n by Ku, ligase D and ligase C
@en
P2093
Alexandra Martins
Chunling Gong
Michael S. Glickman
Nicolas C. Stephanou
Paola Bongiorno
P2860
P2888
P304
P3181
P356
10.1038/NSMB915
P577
2005-04-01T00:00:00Z
P5875
P6179
1029773752