Cloning, expression, and up-regulation of inducible rat prostaglandin e synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis
about
Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthaseMembrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritisContrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prMicrosomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E2Expression of genes controlling transport and catabolism of prostaglandin E2 in lipopolysaccharide feverIntracellular-specific colocalization of prostaglandin E2 synthases and cyclooxygenases in the brainMicrosomal prostaglandin E2 synthase-1 is induced by conditional expression of RET/PTC in thyroid PCCL3 cells through the activation of the MEK-ERK pathway.Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background.Prostaglandin E2 synthases in neurologic homeostasis and diseaseNovel human mPGES-1 inhibitors identified through structure-based virtual screening.Identification and development of mPGES-1 inhibitors: where we are at?Despite transcriptional and functional coordination, cyclooxygenase-2 and microsomal prostaglandin E synthase-1 largely reside in distinct lipid microdomains in WISH epithelial cellsProstaglandins and inflammation.Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis.Human microsomal prostaglandin E synthase-1: purification, functional characterization, and projection structure determination.Lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 mediates late-phase PGE2 production in bone marrow derived macrophages.Effects of acetaminophen on constitutive and inducible prostanoid biosynthesis in human blood cells.Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases.COX-2 but not mPGES-1 contributes to renal PGE2 induction and diabetic proteinuria in mice with type-1 diabetes.Prostaglandin E(2) produced by the lung augments the effector phase of allergic inflammation.Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice.Glutathione s-transferases in pediatric cancer.Intracellular signal transduction and modification of the tumor microenvironment induced by RET/PTCs in papillary thyroid carcinoma.Inhibition of STAT3- and MAPK-dependent PGE2 synthesis ameliorates phagocytosis of fibrillar β-amyloid peptide (1-42) via EP2 receptor in EMF-stimulated N9 microglial cells.mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis.Microsomal prostaglandin E synthase-1, ephrins, and ephrin kinases as suspected therapeutic targets in arthritis: exposed by "criminal profiling".Fast synaptic inhibition in spinal sensory processing and pain control.PAMAM dendrimers as nano carriers to investigate inflammatory responses induced by pulmonary exposure of PCB metabolites in Sprague-Dawley ratsmPGES-1 deletion impairs diuretic response to acute water loading.Differential expression of genes in milk of dairy cattle during lactation.Prostaglandin E(2) synthase inhibition as a therapeutic target.Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents.Microsomal prostaglandin e synthase-1 in rheumatic diseases.Persisting eicosanoid pathways in rheumatic diseases.Inhibitors of microsomal prostaglandin E2 synthase-1 enzyme as emerging anti-inflammatory candidates.Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1.Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.A Novel Multi-step Virtual Screening for the Identification of Human and Mouse mPGES-1 Inhibitors.Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors.
P2860
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P2860
Cloning, expression, and up-regulation of inducible rat prostaglandin e synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis
description
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Februar 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/02/09)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/02/09)
@nl
наукова стаття, опублікована в лютому 2001
@uk
name
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@ast
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@en
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@nl
type
label
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@ast
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@en
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@nl
prefLabel
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@ast
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@en
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@nl
P2093
P356
P1476
Cloning, expression, and up-re ...... and adjuvant-induced arthritis
@en
P2093
C. C. Chan
D. Claveau
D. Riendeau
J. A. Mancini
P304
P356
10.1074/JBC.M006865200
P407
P577
2001-02-09T00:00:00Z