RecQ helicases: guardian angels of the DNA replication fork.
about
Rothmund-Thomson syndromeRif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replicationDual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndromePolyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stressRecQ helicase translocates along single-stranded DNA with a moderate processivity and tight mechanochemical couplingRoles of Werner syndrome protein in protection of genome integrityRoles of RECQ helicases in recombination based DNA repair, genomic stability and agingMore complexity to the Bloom's syndrome complexRMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stabilityNucleases in homologous recombination as targets for cancer therapyReplication proteins and human diseaseTopoisomerase II is required for the proper separation of heterochromatic regions during Drosophila melanogaster female meiosisHeterochromatic threads connect oscillating chromosomes during prometaphase I in Drosophila oocytesCrystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complexThe DNA Damage Response: Making It Safe to Play with KnivesAn N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break endsThe role of the Fanconi anemia network in the response to DNA replication stress.DNA replication arrest leads to enhanced homologous recombination and cell death in meristems of rice OsRecQl4 mutants.Role of Genetic Factors in the Pathogenesis of Radial Deficiencies in Humans.dRecQ4 is required for DNA synthesis and essential for cell proliferation in Drosophila.Identification of SMARCAL1 as a component of the DNA damage response.TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei.Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiationBreak-induced replication repair of damaged forks induces genomic duplications in human cells.The DNA/RNA-dependent RNA polymerase QDE-1 generates aberrant RNA and dsRNA for RNAi in a process requiring replication protein A and a DNA helicase.The roles of the Saccharomyces cerevisiae RecQ helicase SGS1 in meiotic genome surveillance.The UvrD303 hyper-helicase exhibits increased processivity.RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase.Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding.Identification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation.The role of post-translational modifications in fine-tuning BLM helicase function during DNA repairThe mutation spectrum in RECQL4 diseases.Time to bloom.microRNAs targeting DEAD-box helicases are involved in salinity stress response in rice (Oryza sativa L.).Drosophila RecQ4 is directly involved in both DNA replication and the response to UV damage in S2 cells.The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding.Sgs1 truncations induce genome rearrangements but suppress detrimental effects of BLM overexpression in Saccharomyces cerevisiae.
P2860
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P2860
RecQ helicases: guardian angels of the DNA replication fork.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
RecQ helicases: guardian angels of the DNA replication fork.
@ast
RecQ helicases: guardian angels of the DNA replication fork.
@en
RecQ helicases: guardian angels of the DNA replication fork.
@nl
type
label
RecQ helicases: guardian angels of the DNA replication fork.
@ast
RecQ helicases: guardian angels of the DNA replication fork.
@en
RecQ helicases: guardian angels of the DNA replication fork.
@nl
prefLabel
RecQ helicases: guardian angels of the DNA replication fork.
@ast
RecQ helicases: guardian angels of the DNA replication fork.
@en
RecQ helicases: guardian angels of the DNA replication fork.
@nl
P2860
P1433
P1476
RecQ helicases: guardian angels of the DNA replication fork.
@en
P2093
Csanád Z Bachrati
Ian D Hickson
P2860
P2888
P304
P356
10.1007/S00412-007-0142-4
P577
2008-01-11T00:00:00Z